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A naturally occurring carotenoid, lutein, reduces PDGF and H2O2 signaling and compromises migration in cultured vascular smooth muscle cells

Overview of attention for article published in Journal of Biomedical Science, February 2012
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Title
A naturally occurring carotenoid, lutein, reduces PDGF and H2O2 signaling and compromises migration in cultured vascular smooth muscle cells
Published in
Journal of Biomedical Science, February 2012
DOI 10.1186/1423-0127-19-18
Pubmed ID
Authors

Huey-Ming Lo, Yih-Jeng Tsai, Wen-Yuan Du, Chih-Jen Tsou, Wen-Bin Wu

Abstract

Platelet-derived growth factor (PDGF) is a potent stimulator of growth and motility of vascular smooth muscle cells (VSMCs). Abnormalities of PDGF/PDGF receptor (PDGFR) are thought to contribute to vascular diseases and malignancy. We previously showed that a carotenoid, lycopene, can directly bind to PDGF and affect its related functions in VSMCs. In this study we examined the effect of the other naturally occurring carotenoid, lutein, on PDGF signaling and migration in VSMCs.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 30 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 27%
Researcher 5 17%
Student > Master 3 10%
Student > Bachelor 2 7%
Student > Doctoral Student 2 7%
Other 4 13%
Unknown 6 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 40%
Biochemistry, Genetics and Molecular Biology 4 13%
Medicine and Dentistry 3 10%
Psychology 1 3%
Chemical Engineering 1 3%
Other 0 0%
Unknown 9 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 February 2012.
All research outputs
#17,285,036
of 25,371,288 outputs
Outputs from Journal of Biomedical Science
#752
of 1,100 outputs
Outputs of similar age
#173,087
of 254,134 outputs
Outputs of similar age from Journal of Biomedical Science
#6
of 12 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,100 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one is in the 23rd percentile – i.e., 23% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 254,134 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.