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Economic burden of inpatients infected with Klebsiella pneumoniae carbapenemase

Overview of attention for article published in Einstein (São Paulo), May 2019
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Title
Economic burden of inpatients infected with Klebsiella pneumoniae carbapenemase
Published in
Einstein (São Paulo), May 2019
DOI 10.31744/einstein_journal/2019gs4444
Pubmed ID
Authors

Wendel Mombaque dos Santos, Silvia Regina Secoli

Abstract

To estimate the direct medical costs of drug therapy of Klebsiella pneumoniae carbapenemase (KPC) infection patients in hospital-based context. A cost-of-illness study conducted with a prospective cohort design with hospitalized adults infected by KPC. Data collection was performed using an instrument composed of sociodemographic data, clinical and prescription medication. Estimates of the direct costs associated to each treatment were derived from the payer's perspective, in the case of federal public hospitals from Brazil, and included only drug costs. These costs were based on the average price available at the Brazilian Price Database Health. No discount rate was used for the cost of drugs. The costs are calculate in American Dollar (US$). A total of 120 inpatients participated of this study. The total drug cost of these inpatients was US$ 367,680.85. The systemic antimicrobial group was responsible for 59.5% of total costs. The direct drug cost per patients infected by KPC was conservatively estimated at nearly US$ 4,100.00, and about of 60% of costs occurred during the period of infection. The findings of our study indicate a thoughtful economic hazard posed by KPC that all healthcare sectors have to face. The increasing worldwide incidence of these bacteria represents a growing burden that most health systems are unable to deal with. There is an imperative need to develop protocols and new antimicrobials to treatment of KPC, aiming to rearrange resources to increase the effectiveness of healthcare services.

Twitter Demographics

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Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 35 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 17%
Student > Master 4 11%
Student > Bachelor 4 11%
Student > Postgraduate 3 9%
Professor 3 9%
Other 4 11%
Unknown 11 31%
Readers by discipline Count As %
Medicine and Dentistry 5 14%
Immunology and Microbiology 4 11%
Pharmacology, Toxicology and Pharmaceutical Science 3 9%
Economics, Econometrics and Finance 3 9%
Biochemistry, Genetics and Molecular Biology 2 6%
Other 4 11%
Unknown 14 40%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 May 2019.
All research outputs
#13,326,114
of 15,094,232 outputs
Outputs from Einstein (São Paulo)
#155
of 214 outputs
Outputs of similar age
#221,353
of 264,385 outputs
Outputs of similar age from Einstein (São Paulo)
#6
of 9 outputs
Altmetric has tracked 15,094,232 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 214 research outputs from this source. They receive a mean Attention Score of 2.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.