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Factors associated with treatment for latent tuberculosis in persons living with HIV/AIDS

Overview of attention for article published in Cadernos de Saúde Pública, December 2015
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Title
Factors associated with treatment for latent tuberculosis in persons living with HIV/AIDS
Published in
Cadernos de Saúde Pública, December 2015
DOI 10.1590/0102-311x00154614
Pubmed ID
Authors

Daniela Silva de Aquino, Líbia Cristina Rocha Vilela Moura, Magda Maruza, Adriana Paula da Silva, Ricardo Arraes de Alencar Ximenes, Heloísa Ramos Lacerda, Demócrito de Barros Miranda Filho, Maria de Fátima Pessoa Militão de Albuquerque

Abstract

The aim was to identify factors associated with non-initiation of prophylactic treatment of latent tuberculosis infection (LTBi) in persons living with HIV/AIDS (PLWA), based on a prospective cohort study of PLWA ≥ 18 years of age in two referral services for HIV/AIDS. Of the 232 patients eligible for treatment of LTBi, 69.8% initiated treatment. Following multivariate logistic regression analysis, only treatment in one of the two referral services was associated with non-initiation of treatment for LTBi (p < 0.001). TB incidence in the cohort was 0.6/100 person-years. TB incidence in patients that initiated treatment of LTBi was 0.4/100 person-years, compared to 1.2/100 person-years in those that did not initiate treatment, but the difference was not statistically significant. The study's most interesting finding was that the main factor associated with the likelihood of treatment for LTBi was the health service where the patient was treated.

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Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 16 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 1 6%
Unknown 15 94%
Readers by discipline Count As %
Medicine and Dentistry 1 6%
Unknown 15 94%