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Antimicrobial action of calcium hydroxide-based endodontic sealers after setting, against E. faecalis biofilm

Overview of attention for article published in Brazilian Oral Research, March 2016
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  • Good Attention Score compared to outputs of the same age and source (71st percentile)

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Title
Antimicrobial action of calcium hydroxide-based endodontic sealers after setting, against E. faecalis biofilm
Published in
Brazilian Oral Research, March 2016
DOI 10.1590/1807-3107bor-2016.vol30.0038
Pubmed ID
Authors

Gabriely Cristinni Rezende, Loiane Massunari, India Olinta de Azevedo Queiroz, João Eduardo Gomes Filho, Rogério Castilho Jacinto, Carolina Simonetti Lodi, Elói Dezan Junior

Abstract

Enterococcus faecalis are gram positive bacteria that can mostly resist endodontic therapy, inducing persistent infection in the root canal system. Endodontic sealers with antimicrobial activity may help eliminate residual microorganisms that survive endodontic treatment. The present study aimed at comparing the antimicrobial activity of Acroseal, Sealapex and AH Plus endodontic sealers in an in vitro biofilm model. Bovine dentin specimens (144) were prepared, and twelve blocks for each sealer and each experimental time point (2, 7 and 14 days) were placed and left in contact with plates containing inoculum of E. faecalis (ATCC 51299), to induce biofilm formation. After 14 days, the samples were transferred to another plate with test sealers and kept at 37°C and 5% CO2 for 2, 7 and 14 days. The specimens without sealers were used as a control for each period. The samples were agitated in a sonicator after each experiment. The suspensions were agitated in a vortex mixer, serially diluted in saline, and triple plated onto m-Enterococcus agar. Colonyforming units were counted, and the data were statistically analyzed using ANOVA, Shapiro-Wilk and Kruskal-Wallis one-way tests (p < 0.05) to determine antimicrobial potential. Sealapex showed significant differences at all the experimental time points, in comparison with all the other groups. AH Plus and Acroseal showed antimicrobial activity only on the 14th experimental day. Neither of the sealers tested were able to completely eliminate the biofilm. Sealapex showed the highest antimicrobial activity in all the experimental periods. The antimicrobial activity of all the sealers analyzed increased over time.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 81 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 10%
Student > Postgraduate 7 9%
Student > Ph. D. Student 7 9%
Student > Bachelor 5 6%
Researcher 4 5%
Other 13 16%
Unknown 37 46%
Readers by discipline Count As %
Medicine and Dentistry 29 36%
Agricultural and Biological Sciences 3 4%
Unspecified 2 2%
Immunology and Microbiology 2 2%
Environmental Science 1 1%
Other 4 5%
Unknown 40 49%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 March 2016.
All research outputs
#19,942,887
of 25,371,288 outputs
Outputs from Brazilian Oral Research
#272
of 509 outputs
Outputs of similar age
#217,492
of 313,887 outputs
Outputs of similar age from Brazilian Oral Research
#3
of 28 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 509 research outputs from this source. They receive a mean Attention Score of 2.3. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,887 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.