Title |
Fetal exposure to bisphenol A as a risk factor for the development of childhood asthma: an animal model study
|
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Published in |
Environmental Health, February 2012
|
DOI | 10.1186/1476-069x-11-8 |
Pubmed ID | |
Authors |
Yoichi Nakajima, Randall M Goldblum, Terumi Midoro-Horiuti |
Abstract |
The prevalence of asthma in industrialized countries has been increasing dramatically and asthma is now the most common chronic disease of children in the United States. The rapidity of the increase strongly suggests that changes in environmental exposures are the likely cause of this epidemic. Further, the early onset of allergic manifestations suggests that these exposures may act on the prenatal development of the immune system. We have focused on the potential effects of bisphenol A (BPA), a chemical pollutant with one of the largest productions, on the development of childhood asthma. We have reported that perinatal BPA exposure promotes the development of allergic asthma in a mouse model. The current study was designed to identify a critical period of BPA exposure and to begin elucidating the mechanisms for this susceptibility. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Finland | 1 | <1% |
United States | 1 | <1% |
Nigeria | 1 | <1% |
Canada | 1 | <1% |
Unknown | 97 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 17 | 17% |
Researcher | 15 | 15% |
Student > Bachelor | 13 | 13% |
Student > Ph. D. Student | 11 | 11% |
Student > Postgraduate | 9 | 9% |
Other | 20 | 20% |
Unknown | 16 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 19 | 19% |
Biochemistry, Genetics and Molecular Biology | 14 | 14% |
Agricultural and Biological Sciences | 13 | 13% |
Nursing and Health Professions | 8 | 8% |
Environmental Science | 8 | 8% |
Other | 20 | 20% |
Unknown | 19 | 19% |