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Optogenetics

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Cover of 'Optogenetics'

Table of Contents

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    Book Overview
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    Chapter 1 Optogenetics
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    Chapter 2 Optogenetics
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    Chapter 3 Optogenetics
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    Chapter 4 Reversible Photoregulation of Gene Expression and Translation
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    Chapter 5 Controlling Protein Activity and Degradation Using Blue Light.
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    Chapter 6 Photo Control of Protein Function Using Photoactive Yellow Protein
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    Chapter 7 Optogenetics
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    Chapter 8 Optogenetic Control of Pancreatic Islets
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    Chapter 9 Optogenetics in Plants: Red/Far-Red Light Control of Gene Expression
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    Chapter 10 Optogenetics
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    Chapter 11 Optogenetics
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    Chapter 12 Optogenetic Control of Mammalian Ion Channels with Chemical Photoswitches
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    Chapter 13 Optogenetic Modulation of Locomotor Activity on Free-Behaving Rats
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    Chapter 14 Combined Optogenetic and Chemogenetic Control of Neurons
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    Chapter 15 Intracranial Injection of an Optogenetics Viral Vector Followed by Optical Cannula Implantation for Neural Stimulation in Rat Brain Cortex
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    Chapter 16 An Optimized Calcium-Phosphate Transfection Method for Characterizing Genetically Encoded Tools in Primary Neurons
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    Chapter 17 Optogenetic Approaches for Mesoscopic Brain Mapping
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    Chapter 18 Optogenetic Tools for Confined Stimulation in Deep Brain Structures
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    Chapter 19 Optogenetics
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    Chapter 20 Optogenetic Light Crafting Tools for the Control of Cardiac Arrhythmias
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    Chapter 21 Inscribing Optical Excitability to Non-Excitable Cardiac Cells: Viral Delivery of Optogenetic Tools in Primary Cardiac Fibroblasts
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    Chapter 22 Optogenetic Engineering of Atrial Cardiomyocytes
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    Chapter 23 A Multichannel Recording System with Optical Stimulation for Closed-Loop Optogenetic Experiments
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    Chapter 24 Optogenetic Control of Fibroblast Growth Factor Receptor Signaling
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    Chapter 25 Protein Inactivation by Optogenetic Trapping in Living Cells
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    Chapter 26 Optogenetics
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    Chapter 27 Guidelines for Photoreceptor Engineering
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    Chapter 28 Erratum to: Optogenetics in Plants: Red/Far-Red Light Control of Gene Expression
Attention for Chapter 18: Optogenetic Tools for Confined Stimulation in Deep Brain Structures
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Chapter title
Optogenetic Tools for Confined Stimulation in Deep Brain Structures
Chapter number 18
Book title
Optogenetics
Published in
Methods in molecular biology, March 2016
DOI 10.1007/978-1-4939-3512-3_18
Pubmed ID
Book ISBNs
978-1-4939-3510-9, 978-1-4939-3512-3
Authors

Alexandre Castonguay, Sébastien Thomas, Frédéric Lesage, Christian Casanova

Editors

Arash Kianianmomeni

Abstract

Optogenetics has emerged in the past decade as a technique to modulate brain activity with cell-type specificity and with high temporal resolution. Among the challenges associated with this technique is the difficulty to target a spatially restricted neuron population. Indeed, light absorption and scattering in biological tissues make it difficult to illuminate a minute volume, especially in the deep brain, without the use of optical fibers to guide light. This work describes the design and the in vivo application of a side-firing optical fiber adequate for delivering light to specific regions within a brain subcortical structure.

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 2 25%
Student > Master 1 13%
Librarian 1 13%
Researcher 1 13%
Professor > Associate Professor 1 13%
Other 0 0%
Unknown 2 25%
Readers by discipline Count As %
Neuroscience 3 38%
Engineering 2 25%
Agricultural and Biological Sciences 1 13%
Unknown 2 25%