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Zika virus and neurologic autoimmunity: the putative role of gangliosides

Overview of attention for article published in BMC Medicine, March 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • Average Attention Score compared to outputs of the same age and source

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12 X users
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1 Facebook page

Citations

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53 Dimensions

Readers on

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205 Mendeley
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Title
Zika virus and neurologic autoimmunity: the putative role of gangliosides
Published in
BMC Medicine, March 2016
DOI 10.1186/s12916-016-0601-y
Pubmed ID
Authors

Juan-Manuel Anaya, Carolina Ramirez-Santana, Ignacio Salgado-Castaneda, Christopher Chang, Aftab Ansari, M. Eric Gershwin

Abstract

An increasing number of severe neurological complications associated with Zika virus (ZIKV), chiefly Guillain-Barré syndrome (GBS) and primary microcephaly, have led the World Health Organization to declare a global health emergency. Molecular mimicry between glycolipids and surface molecules of infectious agents explain most of the cases of GBS preceded by infection, while a direct toxicity of ZIKV on neural cells has been raised as the main mechanism by which ZIKV induces microcephaly. Gangliosides are crucial in brain development, and their expression correlates with neurogenesis, synaptogenesis, synaptic transmission, and cell proliferation. Targeting the autoimmune response to gangliosides may represent an underexploited opportunity to examine the increased incidence of neurological complications related to ZIKV infection.

X Demographics

X Demographics

The data shown below were collected from the profiles of 12 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 205 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Colombia 2 <1%
Brazil 2 <1%
France 1 <1%
Switzerland 1 <1%
New Zealand 1 <1%
United States 1 <1%
Unknown 197 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 40 20%
Student > Bachelor 31 15%
Student > Master 27 13%
Student > Ph. D. Student 21 10%
Student > Doctoral Student 15 7%
Other 45 22%
Unknown 26 13%
Readers by discipline Count As %
Medicine and Dentistry 63 31%
Agricultural and Biological Sciences 31 15%
Immunology and Microbiology 16 8%
Biochemistry, Genetics and Molecular Biology 14 7%
Nursing and Health Professions 9 4%
Other 34 17%
Unknown 38 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 October 2017.
All research outputs
#3,875,229
of 23,577,654 outputs
Outputs from BMC Medicine
#2,036
of 3,569 outputs
Outputs of similar age
#60,009
of 301,151 outputs
Outputs of similar age from BMC Medicine
#33
of 53 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,569 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 44.5. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 301,151 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 53 others from the same source and published within six weeks on either side of this one. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.