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Terapia-alvo versus dacarbazina no tratamento de primeira linha do melanoma avançado não cirúrgico e metastático: análise de impacto orçamentário na perspectiva do Sistema Único de Saúde, 2018-2020*

Overview of attention for article published in Epidemiologia e Serviços de Saúde, July 2019
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1 tweeter

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Title
Terapia-alvo versus dacarbazina no tratamento de primeira linha do melanoma avançado não cirúrgico e metastático: análise de impacto orçamentário na perspectiva do Sistema Único de Saúde, 2018-2020*
Published in
Epidemiologia e Serviços de Saúde, July 2019
DOI 10.5123/s1679-49742019000200013
Pubmed ID
Authors

Flávia de Miranda Corrêa, Renata Leborato Guerra, Ricardo Ribeiro Alves Fernandes, Mirian Carvalho de Souza, Ivan Ricardo Zimmermann

Abstract

to estimate the incremental budget impact of target therapy for first-line treatment of advanced non-surgical and metastatic melanoma compared to dacarbazine treatment. budget impact analysis, from the Brazilian National Health System (SUS) perspective; based on demographic data and incidence estimates, the population over a three-year time horizon (2018-2020) was delimited and the direct medical costs were estimated; the reference scenario was treatment with dacarbazine, and the alternative scenarios were target therapy with vemurafenib, dabrafenib, vemurafenib + cobimetinib and dabrafenib + trametinib; uncertainty assessment was conducted through scenario analysis. the incremental budget impact ranged from R$ 451,867,881.00 to R$ 768,860,968.00, representing 0.70 to 1.53% of total SUS annual outpatient drugs expenditure; in best and worst scenario, results ranged from R$ 289,160,835.00 to R$ 1,107,081,926.00. the use of target therapy compared to dacarbazine implies an excessive impact on the budget, this bring unfovorable to its possible incorporation.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 19 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 5 26%
Student > Master 3 16%
Student > Doctoral Student 3 16%
Student > Ph. D. Student 2 11%
Professor 1 5%
Other 2 11%
Unknown 3 16%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 21%
Pharmacology, Toxicology and Pharmaceutical Science 3 16%
Medicine and Dentistry 3 16%
Agricultural and Biological Sciences 2 11%
Nursing and Health Professions 2 11%
Other 2 11%
Unknown 3 16%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 July 2019.
All research outputs
#13,571,396
of 15,380,847 outputs
Outputs from Epidemiologia e Serviços de Saúde
#178
of 251 outputs
Outputs of similar age
#218,417
of 261,759 outputs
Outputs of similar age from Epidemiologia e Serviços de Saúde
#1
of 1 outputs
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So far Altmetric has tracked 251 research outputs from this source. They receive a mean Attention Score of 1.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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