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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Azoospermia in rabbits following an intravas injection of Vasalgel ™
|
|---|---|
| Published in |
Basic and Clinical Andrology, March 2016
|
| DOI | 10.1186/s12610-016-0033-8 |
| Pubmed ID | |
| Authors |
Donald Waller, David Bolick, Elaine Lissner, Christopher Premanandan, Gary Gamerman |
| Abstract |
Vasectomy is currently the only long-acting contraceptive option available for men, despite increasing demand and potentially significant positive impacts on human health of additional male contraceptive options. Vasalgel ™ is a high molecular weight hydrogel polymer being developed as a non-hormonal long-acting reversible male contraceptive. Vasalgel consists of styrene-alt-maleic acid dissolved in dimethyl sulfoxide, which is distinct from styrene-alt-maleic anhydride materials previously studied. The goal of the study was to determine the contraceptive efficacy of two test articles with different levels of styrene maleic acid (100 %, and 80 % acid/20 % anhydride). The test articles were injected bilaterally in the vasa deferentia of mature male rabbits. Post-implantation analyses of semen parameters were completed over a 12 month period and compared to baseline measures of sperm concentration, motility and forward progression. Both test articles were effective in blocking the passage of spermatozoa through the vasa deferentia in the 12 subjects completing the study. A significant decrease in sperm concentration occurred following implantation of the test material, with no measurable sperm concentration except for a few samples in one animal that were markedly oligospermic. Vasalgel produced a rapid onset of azoospermia, with no sperm in semen samples collected as early as 29-36 days post-implantation, and was durable over a 12 month period. This study indicated that Vasalgel is an effective non-hormonal long-acting male contraceptive in a rabbit model. |
X Demographics
The data shown below were collected from the profiles of 13 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 38% |
| Greece | 1 | 8% |
| United Kingdom | 1 | 8% |
| Colombia | 1 | 8% |
| Unknown | 5 | 38% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 10 | 77% |
| Practitioners (doctors, other healthcare professionals) | 1 | 8% |
| Scientists | 1 | 8% |
| Science communicators (journalists, bloggers, editors) | 1 | 8% |
Mendeley readers
The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 64 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 16 | 25% |
| Student > Master | 6 | 9% |
| Student > Ph. D. Student | 4 | 6% |
| Professor > Associate Professor | 3 | 5% |
| Unspecified | 2 | 3% |
| Other | 5 | 8% |
| Unknown | 28 | 44% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 9 | 14% |
| Medicine and Dentistry | 8 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 5% |
| Biochemistry, Genetics and Molecular Biology | 3 | 5% |
| Unspecified | 2 | 3% |
| Other | 10 | 16% |
| Unknown | 29 | 45% |
Attention Score in Context
This research output has an Altmetric Attention Score of 464. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 October 2023.
All research outputs
#59,514
of 25,959,914 outputs
Outputs from Basic and Clinical Andrology
#3
of 164 outputs
Outputs of similar age
#1,104
of 318,208 outputs
Outputs of similar age from Basic and Clinical Andrology
#1
of 2 outputs
Altmetric has tracked 25,959,914 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 164 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 24.2. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 318,208 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them