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The relationship between central and peripheral oxytocin concentrations: a systematic review and meta-analysis protocol

Overview of attention for article published in Systematic Reviews, March 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)
  • Good Attention Score compared to outputs of the same age and source (76th percentile)

Mentioned by

blogs
1 blog
twitter
8 tweeters

Citations

dimensions_citation
19 Dimensions

Readers on

mendeley
71 Mendeley
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Title
The relationship between central and peripheral oxytocin concentrations: a systematic review and meta-analysis protocol
Published in
Systematic Reviews, March 2016
DOI 10.1186/s13643-016-0225-5
Pubmed ID
Authors

Mathias Valstad, Gail A. Alvares, Ole A. Andreassen, Lars T. Westlye, Daniel S. Quintana

Abstract

Research examining the effects of oxytocin (OT) interventions on psychiatric, social-behavioral, and social-cognitive outcomes regularly collect peripheral levels of OT as markers of central bioavailability. Such inferences rest on the assumption that central and peripheral levels of OT are directly associated. However, conflicting evidence from coordinated sampling of central and peripheral OT question the validity of this assumption. The purpose of this meta-analysis is to evaluate the correlation between central and peripheral OT, as well as to account for potential heterogeneity in the literature. Studies that report coordinated sampling of central and peripheral OT in humans and animals will be identified. Research investigating concentrations in both basal states and after exogenous administration will be considered. PubMed and Embase databases will be searched, along with citation lists of retrieved articles. Peer-reviewed studies written in English published from 1971 onwards will be included in the meta-analysis. Data will be extracted from eligible studies for a random-effects meta-analysis. For each study, a summary effect size, heterogeneity, risk of bias, publication bias, and the effect of categorical and continuous moderator variables will be determined. This systematic review and meta-analysis will identify and synthesize evidence to determine if there is an association between central and peripheral OT concentrations. If significant associations are observed, evidence would provide a rationale for future research to use peripheral measures as a proxy for central OT concentrations. PROSPERO CRD42015027864.

Twitter Demographics

The data shown below were collected from the profiles of 8 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 71 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 19 27%
Student > Ph. D. Student 13 18%
Student > Doctoral Student 8 11%
Student > Bachelor 7 10%
Student > Master 6 8%
Other 15 21%
Unknown 3 4%
Readers by discipline Count As %
Psychology 24 34%
Agricultural and Biological Sciences 11 15%
Medicine and Dentistry 10 14%
Neuroscience 7 10%
Biochemistry, Genetics and Molecular Biology 4 6%
Other 10 14%
Unknown 5 7%

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 November 2018.
All research outputs
#1,450,198
of 13,945,384 outputs
Outputs from Systematic Reviews
#309
of 1,206 outputs
Outputs of similar age
#37,480
of 263,768 outputs
Outputs of similar age from Systematic Reviews
#6
of 26 outputs
Altmetric has tracked 13,945,384 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,206 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.3. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 263,768 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 26 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.