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Endothelial nitric oxide synthase: a potential therapeutic target for cerebrovascular diseases

Overview of attention for article published in Molecular Brain, March 2016
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Title
Endothelial nitric oxide synthase: a potential therapeutic target for cerebrovascular diseases
Published in
Molecular Brain, March 2016
DOI 10.1186/s13041-016-0211-9
Pubmed ID
Authors

Jinqiang Zhu, Wanshan Song, Lin Li, Xiang Fan

Abstract

Endothelial nitric oxide (NO) is a significant signaling molecule that regulates cerebral blood flow (CBF), playing a pivotal role in the prevention and treatment of cerebrovascular diseases. However, achieving the expected therapeutic efficacy is difficult using direct administration of NO donors. Therefore, endothelial nitric oxide synthase (eNOS) becomes a potential therapeutic target for cerebrovascular diseases. This review summarizes the current evidence supporting the importance of CBF to cerebrovascular function, and the roles of NO and eNOS in CBF regulation.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 96 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Unknown 95 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 16%
Student > Bachelor 15 16%
Researcher 14 15%
Student > Master 6 6%
Student > Doctoral Student 5 5%
Other 12 13%
Unknown 29 30%
Readers by discipline Count As %
Medicine and Dentistry 17 18%
Agricultural and Biological Sciences 14 15%
Biochemistry, Genetics and Molecular Biology 11 11%
Neuroscience 9 9%
Pharmacology, Toxicology and Pharmaceutical Science 6 6%
Other 12 13%
Unknown 27 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 April 2016.
All research outputs
#20,655,488
of 25,371,288 outputs
Outputs from Molecular Brain
#924
of 1,198 outputs
Outputs of similar age
#234,236
of 314,382 outputs
Outputs of similar age from Molecular Brain
#32
of 35 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,198 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 314,382 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.