Le clivage de tau par Casp2 favorise la localisation anormale de tau dans les épines dendritiques, entraînant une réduction du R.AMPA postsyn. et de la transmission excitatrice, suggérant un dysfonctionnement synaptique ...et des tr. cognitifs dans la LBD
875 followers
875 followers
"Cleavage of tau by Casp2 promotes the mislocalization of tau to dendritic spines leading to a reduction in postsynaptic AMPA R. and excitatory neurotransmission, which suggests a mechanism of the synaptic dysfunction ...and cognitive impairment" in LBD ht
11 followers
RT @knelsonphd: Happy to see our latest publication on a potential target for dementias! Proud of all our group's work. https://t.co/p4ooct…
185 followers
Happy to see our latest publication on a potential target for dementias! Proud of all our group's work. https://t.co/p4ooctZl4i