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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Therapeutic use of a cationic antimicrobial peptide from the spider Acanthoscurria gomesianain the control of experimental candidiasis
|
|---|---|
| Published in |
BMC Microbiology, March 2012
|
| DOI | 10.1186/1471-2180-12-28 |
| Pubmed ID | |
| Authors |
Diego C Rossi, Julian E Muñoz, Danielle D Carvalho, Rodrigo Belmonte, Bluma Faintuch, Primavera Borelli, Antonio Miranda, Carlos P Taborda, Sirlei Daffre |
| Abstract |
Antimicrobial peptides are present in animals, plants and microorganisms and play a fundamental role in the innate immune response. Gomesin is a cationic antimicrobial peptide purified from haemocytes of the spider Acanthoscurria gomesiana. It has a broad-spectrum of activity against bacteria, fungi, protozoa and tumour cells. Candida albicans is a commensal yeast that is part of the human microbiota. However, in immunocompromised patients, this fungus may cause skin, mucosal or systemic infections. The typical treatment for this mycosis comprises three major categories of antifungal drugs: polyenes, azoles and echinocandins; however cases of resistance to these drugs are frequently reported. With the emergence of microorganisms that are resistant to conventional antibiotics, the development of alternative treatments for candidiasis is important. In this study, we evaluate the efficacy of gomesin treatment on disseminated and vaginal candidiasis as well as its toxicity and biodistribution. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 82 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 1% |
| Unknown | 81 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 14 | 17% |
| Student > Bachelor | 13 | 16% |
| Researcher | 10 | 12% |
| Student > Ph. D. Student | 10 | 12% |
| Student > Doctoral Student | 8 | 10% |
| Other | 18 | 22% |
| Unknown | 9 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 19 | 23% |
| Biochemistry, Genetics and Molecular Biology | 16 | 20% |
| Immunology and Microbiology | 11 | 13% |
| Medicine and Dentistry | 11 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 5% |
| Other | 12 | 15% |
| Unknown | 9 | 11% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 March 2012.
All research outputs
#18,305,470
of 22,663,969 outputs
Outputs from BMC Microbiology
#2,219
of 3,162 outputs
Outputs of similar age
#121,027
of 156,118 outputs
Outputs of similar age from BMC Microbiology
#16
of 19 outputs
Altmetric has tracked 22,663,969 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,162 research outputs from this source. They receive a mean Attention Score of 4.1. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 156,118 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.