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Effect of Simulated Geomagnetic Activity on Myocardial Ischemia/Reperfusion Injury in Rats

Overview of attention for article published in Brazilian journal of cardiovascular surgery, January 2019
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Title
Effect of Simulated Geomagnetic Activity on Myocardial Ischemia/Reperfusion Injury in Rats
Published in
Brazilian journal of cardiovascular surgery, January 2019
DOI 10.21470/1678-9741-2018-0306
Pubmed ID
Authors

Hui Wu, Weiyu Chang, Yanglin Deng, Xinli Chen, Yongli Ding, Xuesong Li, Liang Dong

Abstract

To study the response of myocardial ischemia/reperfusion injury (MI/RI) in rats to simulated geomagnetic activity. In a simulated strong geomagnetic outbreak, the MI/RI rat models were radiated, and their area of myocardial infarction, hemodynamic parameters, creatine kinase (CK), lactate dehydrogenase (LDH), melatonin, and troponin I values were measured after a 24-hour intervention. Our analysis indicates that the concentrations of troponin I in the geomagnetic shielding+operation group were lower than in the radiation+operation group (P<0.05), the concentrations of melatonin in the shielding+operation group and normal+operation group were higher than in the radiation + operation group (P<0.01), and the concentrations of CK in the shielding + operation group were lower than in the radiation + operation group and normal + operation group (P<0.05). Left ventricular developed pressure (LVDP) and ± dP/dtmax in the radiation+operation group were lower than in the shielding + operation group and normal+operation group (P<0.01). Left ventricular end-diastolic pressure (LEVDP) in the shielding + operation group was higher than in the normal + operation group (P<0.05). There was no significant difference in area of myocardial infarction and LDH between the shielding + operation group and the radiation + operation group. Our data suggest that geomagnetic activity is important in regulating myocardial reperfusion injury. The geomagnetic shielding has a protective effect on myocardial injury, and the geomagnetic radiation is a risk factor for aggravating the cardiovascular and cerebrovascular diseases.

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Mendeley readers

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Geographical breakdown

Country Count As %
Unknown 5 100%

Demographic breakdown

Readers by professional status Count As %
Professor > Associate Professor 1 20%
Student > Postgraduate 1 20%
Student > Master 1 20%
Unknown 2 40%
Readers by discipline Count As %
Nursing and Health Professions 1 20%
Medicine and Dentistry 1 20%
Unknown 3 60%