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Intestinal mucosal barrier function in health and disease

Overview of attention for article published in Nature Reviews Immunology, November 2009
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

Mentioned by

news
2 news outlets
blogs
2 blogs
twitter
1 X user
patent
19 patents
wikipedia
3 Wikipedia pages

Citations

dimensions_citation
2741 Dimensions

Readers on

mendeley
2197 Mendeley
connotea
1 Connotea
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Title
Intestinal mucosal barrier function in health and disease
Published in
Nature Reviews Immunology, November 2009
DOI 10.1038/nri2653
Pubmed ID
Authors

Jerrold R. Turner

Abstract

Mucosal surfaces are lined by epithelial cells. These cells establish a barrier between sometimes hostile external environments and the internal milieu. However, mucosae are also responsible for nutrient absorption and waste secretion, which require a selectively permeable barrier. These functions place the mucosal epithelium at the centre of interactions between the mucosal immune system and luminal contents, including dietary antigens and microbial products. Recent advances have uncovered mechanisms by which the intestinal mucosal barrier is regulated in response to physiological and immunological stimuli. Here I discuss these discoveries along with evidence that this regulation shapes mucosal immune responses in the gut and, when dysfunctional, may contribute to disease.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 2,197 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 15 <1%
United Kingdom 8 <1%
Japan 5 <1%
Ireland 4 <1%
Germany 4 <1%
Argentina 3 <1%
Netherlands 3 <1%
France 2 <1%
Italy 2 <1%
Other 15 <1%
Unknown 2136 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 429 20%
Student > Master 303 14%
Researcher 287 13%
Student > Bachelor 246 11%
Student > Doctoral Student 144 7%
Other 332 15%
Unknown 456 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 537 24%
Medicine and Dentistry 337 15%
Biochemistry, Genetics and Molecular Biology 286 13%
Immunology and Microbiology 178 8%
Pharmacology, Toxicology and Pharmaceutical Science 73 3%
Other 265 12%
Unknown 521 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 49. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 November 2023.
All research outputs
#876,190
of 25,837,817 outputs
Outputs from Nature Reviews Immunology
#396
of 2,693 outputs
Outputs of similar age
#2,239
of 111,803 outputs
Outputs of similar age from Nature Reviews Immunology
#2
of 18 outputs
Altmetric has tracked 25,837,817 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,693 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.0. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 111,803 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.