The National Trauma Institute: Lessons learned in the funding and conduct of sixteen trauma research studies.
Journal of Trauma and Acute Care Surgery, The, April 2016
Price, Michelle A, Beilman, Gregory J, Fabian, Timothy C, Hoyt, David B, Jurkovich, Gregory J, Knudson, M Margaret, MacKenzie, Ellen J, Marshall, Vivienne S, Overton, Kimberly E, Peitzman, Andrew B, Phillips, Monica J, Pruitt, Basil A, Smith, Sharon L, Stewart, Ronald M, Jenkins, Donald H, , , Price, Michelle A., Beilman, Gregory J., Fabian, Timothy C., Hoyt, David B., Jurkovich, Gregory J., Knudson, M. Margaret, MacKenzie, Ellen J., Marshall, Vivienne S., Overton, Kimberly E., Peitzman, Andrew B., Phillips, Monica J., Pruitt, Basil A. Jr., Smith, Sharon L., Stewart, Ronald M., Jenkins, Donald H., National Trauma Institute Research Group
In order to increase trauma-related research and elevate trauma on the national research agenda, the National Trauma Institute (NTI) issued calls for proposals, selected funding recipients and coordinated sixteen federally funded (Department of Defense [DoD]) trauma research awards over a four-year period. We sought to collect and describe the lessons learned from this activity in order to inform future researchers of barriers and facilitators. Fifteen principal investigators participated in semi-structured interviews focused on study management issues such as securing institutional approvals, screening and enrollment, multi-site trials management, project funding, staffing and institutional support. NTI Science Committee meeting minutes and study management data were included in the analysis. Simple descriptive statistics were generated and textual data were analyzed for common themes. PIs reported challenges in obtaining institutional approvals, delays in study initiation, screening and enrollment, multi-site management and study funding. Most were able to successfully resolve challenges and have been productive in terms of scholarly publications, securing additional research funding and training future trauma investigators. Lessons learned in the conduct of the first two funding rounds managed by NTI are instructive in four key areas: regulatory processes, multi-site coordination, adequate funding and the importance of an established research infrastructure to ensure study success. Recommendations for addressing institution-related and investigator-related challenges are discussed along with ongoing advocacy efforts to secure sustained federal funding of a national trauma research program commensurate with the burden of injury. Not applicable.
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