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Effects of L-carnitine against oxidative stress in human hepatocytes: involvement of peroxisome proliferator-activated receptor alpha

Overview of attention for article published in Journal of Biomedical Science, March 2012
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Title
Effects of L-carnitine against oxidative stress in human hepatocytes: involvement of peroxisome proliferator-activated receptor alpha
Published in
Journal of Biomedical Science, March 2012
DOI 10.1186/1423-0127-19-32
Pubmed ID
Authors

Jin-Lian Li, Qiao-Yun Wang, Hai-Yun Luan, Ze-Chun Kang, Chun-Bo Wang

Abstract

Excessive oxidative stress and lipid peroxidation have been demonstrated to play important roles in the production of liver damage. L-carnitine is a natural substance and acts as a carrier for fatty acids across the inner mitochondrial membrane for subsequent beta-oxidation. It is also an antioxidant that reduces metabolic stress in the cells. Recent years L-carnitine has been proposed for treatment of various kinds of disease, including liver injury. This study was conducted to evaluate the protective effect of L-carnitine against hydrogen peroxide (H2O2)-induced cytotoxicity in a normal human hepatocyte cell line, HL7702.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 91 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
India 1 1%
Italy 1 1%
Australia 1 1%
Unknown 87 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 14%
Researcher 10 11%
Student > Master 10 11%
Student > Doctoral Student 9 10%
Student > Postgraduate 8 9%
Other 26 29%
Unknown 15 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 27 30%
Biochemistry, Genetics and Molecular Biology 15 16%
Medicine and Dentistry 13 14%
Immunology and Microbiology 3 3%
Nursing and Health Professions 2 2%
Other 12 13%
Unknown 19 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 November 2017.
All research outputs
#23,010,126
of 25,654,806 outputs
Outputs from Journal of Biomedical Science
#979
of 1,110 outputs
Outputs of similar age
#157,511
of 173,263 outputs
Outputs of similar age from Journal of Biomedical Science
#13
of 13 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,110 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.2. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 173,263 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.