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Proton MR spectroscopy of tumefactive demyelinating lesions.

Overview of attention for article published in American Journal of Neuroradiology, September 2002
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  • Above-average Attention Score compared to outputs of the same age (59th percentile)

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1 Wikipedia page

Citations

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105 Dimensions

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60 Mendeley
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Title
Proton MR spectroscopy of tumefactive demyelinating lesions.
Published in
American Journal of Neuroradiology, September 2002
Pubmed ID
Authors

Saindane, Amit M, Cha, Soonmee, Law, Meng, Xue, Xiaonan, Knopp, Edmond A, Zagzag, David

Abstract

Tumefactive demyelinating lesions (TDLs) can simulate intracranial neoplasms in clinical presentation and MR imaging appearance, and surgical biopsy is often performed in suspected tumors. Proton MR spectroscopy has been applied in assessing various intracranial diseases and is increasingly used in diagnosis and clinical management. Our purpose was to determine if multivoxel proton MR spectroscopy can be used to differentiate TDLs and high-grade gliomas. Conventional MR images, proton MR spectra, and medical records were retrospectively reviewed in six patients with TDLs diagnosed by means of biopsy or by documented clinical improvement, with or without supporting laboratory testing and follow-up imaging. Proton MR spectra of 10 high-grade gliomas with similar conventional MR imaging appearances were used for comparison. In contrast-enhancing, central, and perilesional areas of each lesion, peak heights of N-acetylaspartate (NAA), choline (Cho), and creatine (Cr) were measured and the lactate peak noted. Cho/Cr and NAA/Cr ratios of corresponding regions in TDLs and gliomas were compared. No significant differences in mean Cho/Cr ratios were found in the corresponding contrast-enhancing, central, or perilesional areas of TDLs and gliomas. The mean central-region NAA/Cr ratio in gliomas was significantly lower than that of TDLs, but mean NAA/Cr ratios in other regions were not significantly different. A lactate peak was identified in four of six TDLs and three of 10 gliomas. In the cases examined, the NAA/Cr ratio in the central region of TDLs and high-grade gliomas differed significantly. However, overall metabolite profiles of both lesions were similar; this finding emphasizes the need for the cautious interpretation of spectroscopic findings.

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Canada 1 2%
Brazil 1 2%
Unknown 57 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 23%
Student > Ph. D. Student 7 12%
Other 6 10%
Professor 6 10%
Student > Postgraduate 5 8%
Other 21 35%
Unknown 1 2%
Readers by discipline Count As %
Medicine and Dentistry 33 55%
Neuroscience 6 10%
Agricultural and Biological Sciences 5 8%
Engineering 4 7%
Biochemistry, Genetics and Molecular Biology 3 5%
Other 6 10%
Unknown 3 5%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 August 2020.
All research outputs
#5,038,257
of 15,950,766 outputs
Outputs from American Journal of Neuroradiology
#1,479
of 3,940 outputs
Outputs of similar age
#105,304
of 266,798 outputs
Outputs of similar age from American Journal of Neuroradiology
#29
of 42 outputs
Altmetric has tracked 15,950,766 research outputs across all sources so far. This one is in the 48th percentile – i.e., 48% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,940 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 266,798 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.
We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.