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Endocannabinoids

Overview of attention for book
Attention for Chapter 6: Endocannabinoids and the Immune System in Health and Disease.
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#29 of 500)
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

Mentioned by

news
1 news outlet
twitter
18 tweeters
facebook
5 Facebook pages
googleplus
1 Google+ user

Citations

dimensions_citation
14 Dimensions

Readers on

mendeley
58 Mendeley
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Chapter title
Endocannabinoids and the Immune System in Health and Disease.
Chapter number 6
Book title
Endocannabinoids
Published in
Handbook of experimental pharmacology, January 2015
DOI 10.1007/978-3-319-20825-1_6
Pubmed ID
Book ISBNs
978-3-31-920824-4, 978-3-31-920825-1
Authors

Cabral, Guy A, Ferreira, Gabriela A, Jamerson, Melissa J, Guy A. Cabral, Gabriela A. Ferreira, Melissa J. Jamerson

Editors

Roger G. Pertwee

Abstract

Endocannabinoids are bioactive lipids that have the potential to signal through cannabinoid receptors to modulate the functional activities of a variety of immune cells. Their activation of these seven-transmembranal, G protein-coupled receptors sets in motion a series of signal transductional events that converge at the transcriptional level to regulate cell migration and the production of cytokines and chemokines. There is a large body of data that supports a functional relevance for 2-arachidonoylglycerol (2-AG) as acting through the cannabinoid receptor type 2 (CB2R) to inhibit migratory activities for a diverse array of immune cell types. However, unequivocal data that supports a functional linkage of anandamide (AEA) to a cannabinoid receptor in immune modulation remains to be obtained. Endocannabinoids, as typical bioactive lipids, have a short half-life and appear to act in an autocrine and paracrine fashion. Their immediate effective action on immune function may be at localized sites in the periphery and within the central nervous system. It is speculated that endocannabinoids play an important role in maintaining the overall "fine-tuning" of the immune homeostatic balance within the host.

Twitter Demographics

The data shown below were collected from the profiles of 18 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 1 2%
Unknown 57 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 24%
Student > Bachelor 9 16%
Researcher 8 14%
Student > Master 7 12%
Other 4 7%
Other 6 10%
Unknown 10 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 19%
Biochemistry, Genetics and Molecular Biology 10 17%
Neuroscience 8 14%
Pharmacology, Toxicology and Pharmaceutical Science 7 12%
Medicine and Dentistry 5 9%
Other 6 10%
Unknown 11 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 25. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 August 2020.
All research outputs
#868,588
of 16,322,934 outputs
Outputs from Handbook of experimental pharmacology
#29
of 500 outputs
Outputs of similar age
#17,880
of 251,829 outputs
Outputs of similar age from Handbook of experimental pharmacology
#1
of 7 outputs
Altmetric has tracked 16,322,934 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 500 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 251,829 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them