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Gene expression study using real-time PCR identifies an NTR gene as a major marker of resistance to benznidazole in Trypanosoma cruzi

Overview of attention for article published in Parasites & Vectors, September 2011
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1 X user

Citations

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Title
Gene expression study using real-time PCR identifies an NTR gene as a major marker of resistance to benznidazole in Trypanosoma cruzi
Published in
Parasites & Vectors, September 2011
DOI 10.1186/1756-3305-4-169
Pubmed ID
Authors

Ana M Mejía-Jaramillo, Geysson J Fernández, Lina Palacio, Omar Triana-Chávez

Abstract

Chagas disease is a neglected illness, with limited treatments, caused by the parasite Trypanosoma cruzi. Two drugs are prescribed to treat the disease, nifurtimox and benznidazole, which have been previously reported to have limited efficacy and the appearance of resistance by T. cruzi. Acquisition of drug-resistant phenotypes is a complex physiological process based on single or multiple changes of the genes involved, probably in its mechanisms of action.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 114 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 2%
Colombia 1 <1%
India 1 <1%
Unknown 110 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 26 23%
Researcher 19 17%
Student > Master 15 13%
Student > Bachelor 9 8%
Student > Doctoral Student 9 8%
Other 21 18%
Unknown 15 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 44 39%
Biochemistry, Genetics and Molecular Biology 20 18%
Medicine and Dentistry 10 9%
Pharmacology, Toxicology and Pharmaceutical Science 8 7%
Chemistry 4 4%
Other 8 7%
Unknown 20 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 April 2012.
All research outputs
#15,242,847
of 22,664,267 outputs
Outputs from Parasites & Vectors
#3,351
of 5,427 outputs
Outputs of similar age
#87,847
of 125,604 outputs
Outputs of similar age from Parasites & Vectors
#22
of 28 outputs
Altmetric has tracked 22,664,267 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,427 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 125,604 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.