↓ Skip to main content

Antistaphylococcal activity of bacteriophage derived chimeric protein P128

Overview of attention for article published in BMC Microbiology, January 2012
Altmetric Badge

About this Attention Score

  • Average Attention Score compared to outputs of the same age

Mentioned by

twitter
1 tweeter

Citations

dimensions_citation
37 Dimensions

Readers on

mendeley
52 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Antistaphylococcal activity of bacteriophage derived chimeric protein P128
Published in
BMC Microbiology, January 2012
DOI 10.1186/1471-2180-12-41
Pubmed ID
Authors

Aradhana A Vipra, Srividya N Desai, Panchali Roy, Raghu Patil, Juliet M Raj, Nagalakshmi Narasimhaswamy, Vivek D Paul, Ravisha Chikkamadaiah, Bharathi Sriram

Abstract

Bacterial drug resistance is one of the most significant challenges to human health today. In particular, effective antibacterial agents against methicillin-resistant Staphylococcus aureus (MRSA) are urgently needed. A causal relationship between nasal commensal S. aureus and infection has been reported. Accordingly, elimination of nasal S. aureus reduces the risk of infection. Enzymes that degrade bacterial cell walls show promise as antibacterial agents. Bacteriophage-encoded bacterial cell wall-degrading enzymes exhibit intrinsic bactericidal activity. P128 is a chimeric protein that combines the lethal activity of the phage tail-associated muralytic enzyme of Phage K and the staphylococcal cell wall targeting-domain (SH3b) of lysostaphin.Here we report results of in vitro studies evaluating the susceptibility of staphylococcal strains to this novel protein.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Nepal 1 2%
India 1 2%
Unknown 49 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 19%
Researcher 9 17%
Student > Master 9 17%
Other 4 8%
Professor > Associate Professor 4 8%
Other 11 21%
Unknown 5 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 25 48%
Biochemistry, Genetics and Molecular Biology 9 17%
Pharmacology, Toxicology and Pharmaceutical Science 4 8%
Immunology and Microbiology 4 8%
Engineering 2 4%
Other 3 6%
Unknown 5 10%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 April 2012.
All research outputs
#7,761,997
of 12,372,276 outputs
Outputs from BMC Microbiology
#987
of 1,804 outputs
Outputs of similar age
#64,627
of 117,828 outputs
Outputs of similar age from BMC Microbiology
#3
of 8 outputs
Altmetric has tracked 12,372,276 research outputs across all sources so far. This one is in the 23rd percentile – i.e., 23% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,804 research outputs from this source. They receive a mean Attention Score of 3.8. This one is in the 36th percentile – i.e., 36% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 117,828 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.