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Antistaphylococcal activity of bacteriophage derived chimeric protein P128

Overview of attention for article published in BMC Microbiology, March 2012
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (68th percentile)
  • Good Attention Score compared to outputs of the same age and source (65th percentile)

Mentioned by

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1 X user
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1 patent

Citations

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53 Dimensions

Readers on

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75 Mendeley
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Title
Antistaphylococcal activity of bacteriophage derived chimeric protein P128
Published in
BMC Microbiology, March 2012
DOI 10.1186/1471-2180-12-41
Pubmed ID
Authors

Aradhana A Vipra, Srividya Narayanamurthy Desai, Panchali Roy, Raghu Patil, Juliet Mohan Raj, Nagalakshmi Narasimhaswamy, Vivek Daniel Paul, Ravisha Chikkamadaiah, Bharathi Sriram

Abstract

Bacterial drug resistance is one of the most significant challenges to human health today. In particular, effective antibacterial agents against methicillin-resistant Staphylococcus aureus (MRSA) are urgently needed. A causal relationship between nasal commensal S. aureus and infection has been reported. Accordingly, elimination of nasal S. aureus reduces the risk of infection. Enzymes that degrade bacterial cell walls show promise as antibacterial agents. Bacteriophage-encoded bacterial cell wall-degrading enzymes exhibit intrinsic bactericidal activity. P128 is a chimeric protein that combines the lethal activity of the phage tail-associated muralytic enzyme of Phage K and the staphylococcal cell wall targeting-domain (SH3b) of lysostaphin.Here we report results of in vitro studies evaluating the susceptibility of staphylococcal strains to this novel protein.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Nepal 1 1%
India 1 1%
Unknown 72 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 13 17%
Researcher 12 16%
Student > Ph. D. Student 12 16%
Student > Bachelor 8 11%
Other 5 7%
Other 12 16%
Unknown 13 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 26 35%
Biochemistry, Genetics and Molecular Biology 13 17%
Pharmacology, Toxicology and Pharmaceutical Science 6 8%
Immunology and Microbiology 5 7%
Veterinary Science and Veterinary Medicine 2 3%
Other 7 9%
Unknown 16 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 May 2020.
All research outputs
#6,911,781
of 22,664,267 outputs
Outputs from BMC Microbiology
#763
of 3,162 outputs
Outputs of similar age
#47,312
of 160,668 outputs
Outputs of similar age from BMC Microbiology
#7
of 20 outputs
Altmetric has tracked 22,664,267 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 3,162 research outputs from this source. They receive a mean Attention Score of 4.1. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 160,668 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.