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PALB2: research reaching to clinical outcomes for women with breast cancer

Overview of attention for article published in Hereditary Cancer in Clinical Practice, April 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#3 of 162)
  • High Attention Score compared to outputs of the same age (87th percentile)

Mentioned by

twitter
20 tweeters
facebook
1 Facebook page

Citations

dimensions_citation
20 Dimensions

Readers on

mendeley
33 Mendeley
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Title
PALB2: research reaching to clinical outcomes for women with breast cancer
Published in
Hereditary Cancer in Clinical Practice, April 2016
DOI 10.1186/s13053-016-0049-2
Pubmed ID
Authors

Melissa C. Southey, Ingrid Winship, Tú Nguyen-Dumont, Southey, Melissa C, Winship, Ingrid, Nguyen-Dumont, Tú

Abstract

PALB2 has taken its place with bona fide breast cancer susceptibility genes. It is now well established that women who carry loss-of-function mutations in the PALB2 gene are at similarly elevated breast cancer risks to those who carry mutations in BRCA2. Information about PALB2 is now being used in breast cancer clinical genetics practice and is routinely included in breast cancer predisposition gene panel tests. Tens of thousands of women worldwide have now had genetic tests for PALB2 mutations in the context of breast cancer susceptibility. However, prospective data related to the clinical outcomes of PALB2 mutation carriers is lacking and very little information (beyond mutation penetrance) is available to guide current clinical management for carriers (affected and unaffected by cancer). In addition, clinical classification of the vast array of non-loss-of-function genetic variants identified in PALB2 is in its infancy. These are key areas of current research efforts and are important foundations on which to move information about PALB2 into the precision public health arena.

Twitter Demographics

The data shown below were collected from the profiles of 20 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
Unknown 32 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 30%
Student > Ph. D. Student 5 15%
Other 4 12%
Researcher 4 12%
Student > Bachelor 3 9%
Other 5 15%
Unknown 2 6%
Readers by discipline Count As %
Medicine and Dentistry 11 33%
Biochemistry, Genetics and Molecular Biology 10 30%
Agricultural and Biological Sciences 5 15%
Nursing and Health Professions 1 3%
Neuroscience 1 3%
Other 1 3%
Unknown 4 12%

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 April 2017.
All research outputs
#1,484,256
of 15,542,562 outputs
Outputs from Hereditary Cancer in Clinical Practice
#3
of 162 outputs
Outputs of similar age
#34,063
of 265,511 outputs
Outputs of similar age from Hereditary Cancer in Clinical Practice
#1
of 1 outputs
Altmetric has tracked 15,542,562 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 162 research outputs from this source. They receive a mean Attention Score of 2.6. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 265,511 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them