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Effectiveness of blended depression treatment for adults in specialised mental healthcare: study protocol for a randomised controlled trial

Overview of attention for article published in BMC Psychiatry, April 2016
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Title
Effectiveness of blended depression treatment for adults in specialised mental healthcare: study protocol for a randomised controlled trial
Published in
BMC Psychiatry, April 2016
DOI 10.1186/s12888-016-0818-5
Pubmed ID
Authors

L. L. Kemmeren, D. J. F. van Schaik, H. Riper, A. M. Kleiboer, J. E. Bosmans, J. H. Smit

Abstract

Internet-based interventions are seen as an important potential strategy to improve accessibility and affordability of high quality treatments in mental healthcare. A growing number of studies have demonstrated the clinical efficacy of internet-based treatment for mood disorders, but scientific evidence for the application in routine specialised mental healthcare settings is limited. Also, little is known about the clinical and health-economic benefits of blended treatment, where online interventions are integrated with face-to-face treatment of depression in one treatment protocol. The primary aim of this study is to investigate the clinical and cost-effectiveness of blended Cognitive Behavioural Therapy (bCBT) for depression, as compared to treatment as usual (TAU) in specialised routine mental healthcare in the Netherlands. This trial is part of the E-COMPARED project which has a broader perspective, focussing on primary and specialised care in eight European countries. The study is a randomised controlled non-inferiority trial with two parallel conditions: bCBT and TAU. The blended treatment combines individual face-to-face CBT with CBT delivered through an Internet-based treatment platform (Moodbuster). This platform includes a mobile phone application, used for ecological momentary assessments, automated feedback and motivational messages. Weekly alternating face-to-face (10) and online (9) sessions will be delivered over a period of 19-20 weeks. TAU is defined as the routine care that subjects receive when they are diagnosed with depression in specialised mental healthcare. Adult patients ≥ 18 years old meeting DSM-IV diagnostic criteria for major depressive disorder will be recruited within participating outpatient specialised mental healthcare clinics in the Netherlands. Measurements will be taken at baseline and at 3, 6 and 12 months follow-up. The primary outcome will be depressive symptoms, measured with the PHQ-9 and QIDS. Secondary outcomes include health-related quality of life, mastery, treatment preference, working alliance, system usability, treatment satisfaction and possible negative side-effects. Moreover, a cost-effectiveness analysis will be conducted from a societal perspective and will include both direct and indirect healthcare costs. The results of this study will provide insight into the health and economical outcomes of blended treatment for depression and give an indication of the value of implementing blended treatment in specialised clinical settings. Netherlands Trial Register NTR4962 . Registered 05-01-2015.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 303 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Colombia 1 <1%
Brazil 1 <1%
Sweden 1 <1%
South Africa 1 <1%
United Kingdom 1 <1%
Unknown 298 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 52 17%
Student > Ph. D. Student 46 15%
Student > Bachelor 34 11%
Researcher 32 11%
Student > Doctoral Student 14 5%
Other 46 15%
Unknown 79 26%
Readers by discipline Count As %
Psychology 109 36%
Medicine and Dentistry 35 12%
Nursing and Health Professions 15 5%
Social Sciences 15 5%
Computer Science 10 3%
Other 32 11%
Unknown 87 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 April 2016.
All research outputs
#17,799,386
of 22,865,319 outputs
Outputs from BMC Psychiatry
#3,685
of 4,698 outputs
Outputs of similar age
#205,342
of 299,499 outputs
Outputs of similar age from BMC Psychiatry
#79
of 111 outputs
Altmetric has tracked 22,865,319 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,698 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.9. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 299,499 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 111 others from the same source and published within six weeks on either side of this one. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.