| Chapter title |
Vaccine Design
|
|---|---|
| Chapter number | 35 |
| Book title |
Vaccine Design
|
| Published in |
Methods in molecular biology, January 2016
|
| DOI | 10.1007/978-1-4939-3387-7_35 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-3385-3, 978-1-4939-3387-7
|
| Authors |
Gannavaram, Sreenivas, Bhattacharya, Parna, Dey, Ranadhir, Ismail, Nevien, Avishek, Kumar, Salotra, Poonam, Selvapandiyan, Angamuthu, Satoskar, Abhay, Nakhasi, Hira L, Sreenivas Gannavaram Ph.D., Parna Bhattacharya, Ranadhir Dey, Nevien Ismail, Kumar Avishek, Poonam Salotra, Angamuthu Selvapandiyan, Abhay Satoskar, Hira L. Nakhasi, Sreenivas Gannavaram |
| Editors |
Sunil Thomas |
| Abstract |
Live-attenuated parasite vaccines are being explored as potential vaccine candidates since other approaches of vaccination have not produced an effective vaccine so far. In order for live-attenuated parasite vaccines to be tested in preclinical studies and possibly in clinical studies, the safety and immunogenicity of these organisms must be rigorously evaluated. Here we describe methods to test persistence in the immunized host and immunogenicity, and to identify biomarkers of vaccine safety and efficacy with particular reference to genetically attenuated Leishmania parasites. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 9 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 2 | 22% |
| Student > Doctoral Student | 1 | 11% |
| Lecturer | 1 | 11% |
| Unknown | 5 | 56% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 2 | 22% |
| Agricultural and Biological Sciences | 1 | 11% |
| Biochemistry, Genetics and Molecular Biology | 1 | 11% |
| Unknown | 5 | 56% |