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Vaccine Design

Overview of attention for book
Cover of 'Vaccine Design'

Table of Contents

  1. Altmetric Badge
    Book Overview
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    Chapter 1 Clinical Impact of Vaccine Development.
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    Chapter 2 Vaccine Design
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    Chapter 3 Vaccine Design
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    Chapter 4 Reverse Vaccinology: The Pathway from Genomes and Epitope Predictions to Tailored Recombinant Vaccines.
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    Chapter 5 Vaccine Design
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    Chapter 6 Vaccine Design
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    Chapter 7 Development of Rabies Virus-Like Particles for Vaccine Applications: Production, Characterization, and Protection Studies.
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    Chapter 8 Analytic Vaccinology: Antibody-Driven Design of a Human Cytomegalovirus Subunit Vaccine.
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    Chapter 9 Generation of a Single-Cycle Replicable Rift Valley Fever Vaccine.
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    Chapter 10 Application of Droplet Digital PCR to Validate Rift Valley Fever Vaccines.
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    Chapter 11 Methods to Evaluate Novel Hepatitis C Virus Vaccines.
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    Chapter 12 Designing Efficacious Vesicular Stomatitis Virus-Vectored Vaccines Against Ebola Virus.
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    Chapter 13 Assessment of Functional Norovirus Antibody Responses by Blocking Assay in Mice.
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    Chapter 14 Development of a SARS Coronavirus Vaccine from Recombinant Spike Protein Plus Delta Inulin Adjuvant.
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    Chapter 15 Generation and Characterization of a Chimeric Tick-Borne Encephalitis Virus Attenuated Strain ChinTBEV.
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    Chapter 16 Vaccine Design
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    Chapter 17 Reverse Genetics Approaches to Control Arenavirus.
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    Chapter 18 DNA Vaccines: A Strategy for Developing Novel Multivalent TB Vaccines.
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    Chapter 19 Vaccine Design
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    Chapter 20 Vaccine Design
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    Chapter 21 Vaccine Design
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    Chapter 22 Murine Models of Bacteremia and Surgical Wound Infection for the Evaluation of Staphylococcus aureus Vaccine Candidates.
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    Chapter 23 Vaccine Design
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    Chapter 24 An Approach to Identify and Characterize a Subunit Candidate Shigella Vaccine Antigen.
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    Chapter 25 Approach to the Discovery, Development, and Evaluation of a Novel Neisseria meningitidis Serogroup B Vaccine.
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    Chapter 26 Vaccine Design
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    Chapter 27 Assessment of Live Plague Vaccine Candidates.
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    Chapter 28 Vaccine Design
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    Chapter 29 Vaccine Design
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    Chapter 30 Vaccine Design
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    Chapter 31 Flow Cytometric Analysis of Protective T-Cell Response Against Pulmonary Coccidioides Infection.
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    Chapter 32 Vaccine Design
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    Chapter 33 Vaccine Design
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    Chapter 34 DNA Integration in Leishmania Genome: An Application for Vaccine Development and Drug Screening.
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    Chapter 35 Vaccine Design
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    Chapter 36 The Use of Microwave-Assisted Solid-Phase Peptide Synthesis and Click Chemistry for the Synthesis of Vaccine Candidates Against Hookworm Infection.
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    Chapter 37 Methods and Protocols for Developing Prion Vaccines.
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    Chapter 38 Ricin-Holotoxin-Based Vaccines: Induction of Potent Ricin-Neutralizing Antibodies.
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    Chapter 39 Synthesis of Hapten-Protein Conjugate Vaccines with Reproducible Hapten Densities.
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    Chapter 40 Production of Rice Seed-Based Allergy Vaccines.
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    Chapter 41 Vaccine Design
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    Chapter 42 Vaccine Design
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    Chapter 43 Vaccine Design
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    Chapter 44 Vaccine Design
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    Chapter 45 T-Cell Epitope Discovery for Therapeutic Cancer Vaccines.
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    Chapter 46 Peptide-Based Cancer Vaccine Strategies and Clinical Results.
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    Chapter 47 Vaccine Design
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    Chapter 48 Development of Antibody-Based Vaccines Targeting the Tumor Vasculature.
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    Chapter 49 Practical Approaches to Forced Degradation Studies of Vaccines.
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    Chapter 50 Erratum.
Attention for Chapter 47: Vaccine Design
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Chapter title
Vaccine Design
Chapter number 47
Book title
Vaccine Design
Published in
Methods in molecular biology, January 2016
DOI 10.1007/978-1-4939-3387-7_47
Pubmed ID
Book ISBNs
978-1-4939-3385-3, 978-1-4939-3387-7
Authors

Batich, Kristen A, Swartz, Adam M, Sampson, John H, Kristen A. Batich, Adam M. Swartz, John H. Sampson M.D., Ph.D., Batich, Kristen A., Swartz, Adam M., Sampson, John H., John H. Sampson

Editors

Sunil Thomas

Abstract

Messenger RNA (mRNA)-transfected dendritic cell (DC) vaccines have been shown to be a powerful modality for eliciting antitumor immune responses in mice and humans; however, their application has not been fully optimized since many of the factors that contribute to their efficacy remain poorly understood. Work stemming from our laboratory has recently demonstrated that preconditioning the vaccine site with a recall antigen prior to the administration of a dendritic cell vaccine creates systemic recall responses and resultantly enhances dendritic cell migration to the lymph nodes with improved antitumor efficacy. This chapter describes the generation of murine mRNA-transfected DC vaccines, as well as a method for vaccine site preconditioning with protein antigen formulations that create potent recall responses.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 36 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 19%
Student > Bachelor 5 14%
Student > Ph. D. Student 4 11%
Student > Master 4 11%
Student > Postgraduate 2 6%
Other 2 6%
Unknown 12 33%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 19%
Environmental Science 4 11%
Medicine and Dentistry 3 8%
Immunology and Microbiology 3 8%
Earth and Planetary Sciences 2 6%
Other 3 8%
Unknown 14 39%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 April 2016.
All research outputs
#15,368,104
of 22,862,742 outputs
Outputs from Methods in molecular biology
#5,349
of 13,127 outputs
Outputs of similar age
#230,929
of 393,645 outputs
Outputs of similar age from Methods in molecular biology
#545
of 1,470 outputs
Altmetric has tracked 22,862,742 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,127 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 393,645 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1,470 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.