Title |
The role of cytokines and hot flashes in perimenopausal depression
|
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Published in |
Annals of General Psychiatry, April 2012
|
DOI | 10.1186/1744-859x-11-9 |
Pubmed ID | |
Authors |
Sokratis E Karaoulanis, Alexandros Daponte, Katerina A Rizouli, Andreas A Rizoulis, Georgios A Lialios, Catherine T Theodoridou, Christos Christakopoulos, Nikiforos V Angelopoulos |
Abstract |
An imbalance in the production of proinflammatory and anti-inflammatory cytokines may play a role in the pathophysiology of perimenopausal depression. The aim of this study was to examine serum levels of the proinflammatory cytokines interleukin 6 (IL-6) and tumor necrosis factor α (TNFα), and the anti-inflammatory cytokine IL-10, in perimenopausal women suffering from depression. Furthermore, to assess whether serum cytokine levels are associated with the presence of hot flashes or the use of selective serotonin reuptake inhibitors (SSRIs). We also evaluated the possible association of hot flashes and perimenopausal depression. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Korea, Republic of | 1 | 3% |
Poland | 1 | 3% |
Unknown | 38 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 6 | 15% |
Researcher | 5 | 13% |
Student > Doctoral Student | 4 | 10% |
Professor | 4 | 10% |
Student > Ph. D. Student | 4 | 10% |
Other | 6 | 15% |
Unknown | 11 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 8 | 20% |
Psychology | 5 | 13% |
Agricultural and Biological Sciences | 4 | 10% |
Neuroscience | 4 | 10% |
Nursing and Health Professions | 3 | 8% |
Other | 5 | 13% |
Unknown | 11 | 28% |