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Mendeley readers
Attention Score in Context
| Title |
Abundance and functional diversity of riboswitches in microbial communities
|
|---|---|
| Published in |
BMC Genomics, October 2007
|
| DOI | 10.1186/1471-2164-8-347 |
| Pubmed ID | |
| Authors |
Marat D Kazanov, Alexey G Vitreschak, Mikhail S Gelfand |
| Abstract |
Several recently completed large-scale enviromental sequencing projects produced a large amount of genetic information about microbial communities ('metagenomes') which is not biased towards cultured organisms. It is a good source for estimation of the abundance of genes and regulatory structures in both known and unknown members of microbial communities. In this study we consider the distribution of RNA regulatory structures, riboswitches, in the Sargasso Sea, Minnesota Soil and Whale Falls metagenomes. Over three hundred riboswitches were found in about 2 Gbp metagenome DNA sequences. The abundabce of riboswitches in metagenomes was highest for the TPP, B12 and GCVT riboswitches; the S-box, RFN, YKKC/YXKD, YYBP/YKOY regulatory elements showed lower but significant abundance, while the LYS, G-box, GLMS and YKOK riboswitches were rare. Regions downstream of identified riboswitches were scanned for open reading frames. Comparative analysis of identified ORFs revealed new riboswitch-regulated functions for several classes of riboswitches. In particular, we have observed phosphoserine aminotransferase serC (COG1932) and malate synthase glcB (COG2225) to be regulated by the glycine (GCVT) riboswitch; fatty acid desaturase ole1 (COG1398), by the cobalamin (B12) riboswitch; 5-methylthioribose-1-phosphate isomerase ykrS (COG0182), by the SAM-riboswitch. We also identified conserved riboswitches upstream of genes of unknown function: thiamine (TPP), cobalamine (B12), and glycine (GCVT, upstream of genes from COG4198). This study demonstrates applicability of bioinformatics to the analysis of RNA regulatory structures in metagenomes. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 116 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 3% |
| India | 2 | 2% |
| Sweden | 1 | <1% |
| Iran, Islamic Republic of | 1 | <1% |
| Netherlands | 1 | <1% |
| Russia | 1 | <1% |
| Mexico | 1 | <1% |
| Spain | 1 | <1% |
| Poland | 1 | <1% |
| Other | 0 | 0% |
| Unknown | 104 | 90% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 32 | 28% |
| Student > Ph. D. Student | 23 | 20% |
| Student > Master | 16 | 14% |
| Student > Doctoral Student | 10 | 9% |
| Professor > Associate Professor | 9 | 8% |
| Other | 18 | 16% |
| Unknown | 8 | 7% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 55 | 47% |
| Biochemistry, Genetics and Molecular Biology | 20 | 17% |
| Physics and Astronomy | 5 | 4% |
| Chemistry | 5 | 4% |
| Environmental Science | 4 | 3% |
| Other | 16 | 14% |
| Unknown | 11 | 9% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 November 2018.
All research outputs
#4,841,279
of 25,394,764 outputs
Outputs from BMC Genomics
#1,877
of 11,250 outputs
Outputs of similar age
#14,058
of 84,466 outputs
Outputs of similar age from BMC Genomics
#6
of 37 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 11,250 research outputs from this source. They receive a mean Attention Score of 4.8. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 84,466 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.