Title |
Atypical DNA methylation of genes encoding cysteine-rich peptides in Arabidopsis thaliana
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Published in |
BMC Plant Biology, April 2012
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DOI | 10.1186/1471-2229-12-51 |
Pubmed ID | |
Authors |
Wanhui You, Agata Tyczewska, Matthew Spencer, Lucia Daxinger, Marc W Schmid, Ueli Grossniklaus, Stacey A Simon, Blake C Meyers, Antonius JM Matzke, Marjori Matzke |
Abstract |
In plants, transposons and non-protein-coding repeats are epigenetically silenced by CG and non-CG methylation. This pattern of methylation is mediated in part by small RNAs and two specialized RNA polymerases, termed Pol IV and Pol V, in a process called RNA-directed DNA methylation. By contrast, many protein-coding genes transcribed by Pol II contain in their gene bodies exclusively CG methylation that is independent of small RNAs and Pol IV/Pol V activities. It is unclear how the different methylation machineries distinguish between transposons and genes. Here we report on a group of atypical genes that display in their coding region a transposon-like methylation pattern, which is associated with gene silencing in sporophytic tissues. |
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