Tumor growth activity of duloxetine in Ehrlich carcinoma in mice

https://t.co/t4W4RtWa3Y "Due to its analgesic effect, Duloxetine can be regarded as an adjuvant option for cancer pain management."

https://t.co/t4W4RtWa3Y "In addition, there was a lower number of CD4+ and CD8+ T cells expressing the CD28 receptor with duloxetine. CD28 hinders cellular energy production."

https://t.co/t4W4RtWa3Y "The number of T lymphocytes stained with the CD3 antibody (CD4+ T and CD8+ T cells) was lower with duloxetine. CD4+ and CD8+ T lymphocytes destroy tumor cells."

https://t.co/t4W4RtWa3Y "Finally, the expression of the costimulatory molecule CD28 in both T helper lymphocyte (T CD4) and cytotoxic T lymphocyte (T CD8) lymphocytes was lower in the Duloxetine groups."