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Effects of zinc supplementation on diabetes mellitus: a systematic review and meta-analysis

Overview of attention for article published in Diabetology & Metabolic Syndrome, April 2012
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#8 of 796)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

news
6 news outlets
blogs
2 blogs
twitter
36 X users
patent
2 patents
facebook
1 Facebook page
googleplus
28 Google+ users
video
4 YouTube creators

Citations

dimensions_citation
271 Dimensions

Readers on

mendeley
369 Mendeley
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Title
Effects of zinc supplementation on diabetes mellitus: a systematic review and meta-analysis
Published in
Diabetology & Metabolic Syndrome, April 2012
DOI 10.1186/1758-5996-4-13
Pubmed ID
Authors

R Jayawardena, P Ranasinghe, P Galappatthy, RLDK Malkanthi, GR Constantine, P Katulanda

Abstract

The number of people with diabetes and pre-diabetes are exponentially increasing. Studies on humans have shown the beneficial effects of Zinc supplementation in patients with diabetes. The present study aims to systematically evaluate the literature and meta-analyze the effects of Zinc supplementation on diabetes. A systematic review of published studies reporting the effects of Zinc supplementations on diabetes mellitus was undertaken. The literature search was conducted in the following databases; PubMed, Web of Science and SciVerse Scopus. A meta-analysis of studies examining the effects of Zinc supplementation on clinical and biochemical parameters in patients with diabetes was performed. The total number of articles included in the present review is 25, which included 3 studies on type-1 diabetes and 22 studies on type-2 diabetes. There were 12 studies comparing the effects of Zinc supplementation on fasting blood glucose in patients with type-2 diabetes. The pooled mean difference in fasting blood glucose between Zinc supplemented and placebo groups was 18.13mg/dl (95%CI:33.85,2.41; p<0.05). 2-h post-prandial blood sugar also shows a similar distinct reduction in (34.87mg/dl [95%CI:75.44; 5.69]) the Zinc treated group. The reduction in HbA1c was 0.54% (95%CI:0.86;0.21) in the Zinc treated group. There were 8 studies comparing the effects of Zinc supplementation on lipid parameters in patients with type-2 diabetes. The pooled mean difference for total cholesterol between Zinc supplemented and placebo groups was 32.37mg/dl (95%CI:57.39,7.35; p<0.05). Low-density lipoprotein cholesterol also showed a similar distinct reduction in the Zinc treated group, the pooled mean difference from random effects analysis was 11.19mg/dl (95%CI:21.14,1.25; p<0.05). Studies have also shown a significant reduction in systolic and diastolic blood pressures after Zinc supplementation. This first comprehensive systematic review and meta-analysis on the effects of Zinc supplementation in patients with diabetes demonstrates that Zinc supplementation has beneficial effects on glycaemic control and promotes healthy lipid parameters. Further studies are required to identify the exact biological mechanisms responsible for these results.

X Demographics

X Demographics

The data shown below were collected from the profiles of 36 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 369 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Australia 3 <1%
Portugal 1 <1%
Germany 1 <1%
Netherlands 1 <1%
Russia 1 <1%
Spain 1 <1%
Croatia 1 <1%
Unknown 360 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 82 22%
Student > Master 61 17%
Student > Ph. D. Student 36 10%
Researcher 30 8%
Other 19 5%
Other 53 14%
Unknown 88 24%
Readers by discipline Count As %
Medicine and Dentistry 107 29%
Agricultural and Biological Sciences 51 14%
Nursing and Health Professions 28 8%
Biochemistry, Genetics and Molecular Biology 27 7%
Pharmacology, Toxicology and Pharmaceutical Science 14 4%
Other 43 12%
Unknown 99 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 114. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 November 2023.
All research outputs
#367,101
of 25,374,917 outputs
Outputs from Diabetology & Metabolic Syndrome
#8
of 796 outputs
Outputs of similar age
#1,588
of 174,277 outputs
Outputs of similar age from Diabetology & Metabolic Syndrome
#2
of 10 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 796 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.8. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 174,277 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 8 of them.