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A comparison of feature selection and classification methods in DNA methylation studies using the Illumina Infinium platform

Overview of attention for article published in BMC Bioinformatics, April 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (89th percentile)

Mentioned by

blogs
1 blog
twitter
3 X users
patent
1 patent

Citations

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97 Dimensions

Readers on

mendeley
193 Mendeley
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3 CiteULike
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Title
A comparison of feature selection and classification methods in DNA methylation studies using the Illumina Infinium platform
Published in
BMC Bioinformatics, April 2012
DOI 10.1186/1471-2105-13-59
Pubmed ID
Authors

Joanna Zhuang, Martin Widschwendter, Andrew E Teschendorff

Abstract

The 27k Illumina Infinium Methylation Beadchip is a popular high-throughput technology that allows the methylation state of over 27,000 CpGs to be assayed. While feature selection and classification methods have been comprehensively explored in the context of gene expression data, relatively little is known as to how best to perform feature selection or classification in the context of Illumina Infinium methylation data. Given the rising importance of epigenomics in cancer and other complex genetic diseases, and in view of the upcoming epigenome wide association studies, it is critical to identify the statistical methods that offer improved inference in this novel context.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 193 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 7 4%
Spain 2 1%
Turkey 1 <1%
France 1 <1%
Norway 1 <1%
United Kingdom 1 <1%
Malaysia 1 <1%
Belgium 1 <1%
Netherlands 1 <1%
Other 2 1%
Unknown 175 91%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 54 28%
Researcher 45 23%
Student > Master 19 10%
Student > Bachelor 15 8%
Student > Postgraduate 11 6%
Other 33 17%
Unknown 16 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 53 27%
Biochemistry, Genetics and Molecular Biology 37 19%
Computer Science 28 15%
Medicine and Dentistry 23 12%
Engineering 8 4%
Other 23 12%
Unknown 21 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 December 2015.
All research outputs
#1,875,113
of 22,664,644 outputs
Outputs from BMC Bioinformatics
#469
of 7,247 outputs
Outputs of similar age
#11,943
of 163,178 outputs
Outputs of similar age from BMC Bioinformatics
#11
of 105 outputs
Altmetric has tracked 22,664,644 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,247 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 163,178 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 105 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.