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Hemoglobin D-Punjab: origin, distribution and laboratory diagnosis

Overview of attention for article published in Revista Brasileira de Hematologia e Hemoterapia, March 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#13 of 259)
  • High Attention Score compared to outputs of the same age (81st percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

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8 tweeters
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1 Wikipedia page

Citations

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27 Dimensions

Readers on

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52 Mendeley
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Title
Hemoglobin D-Punjab: origin, distribution and laboratory diagnosis
Published in
Revista Brasileira de Hematologia e Hemoterapia, March 2015
DOI 10.1016/j.bjhh.2015.02.007
Pubmed ID
Authors

Lidiane de Souza Torres, Jéssika Viviani Okumura, Danilo Grünig Humberto da Silva, Claudia Regina Bonini-Domingos

Abstract

This review discusses hemoglobin D-Punjab, also known as hemoglobin D-Los Angeles, one of the most common hemoglobin variants worldwide. It is derived from a point mutation in the beta-globin gene (HBB: c.364G>C; rs33946267) prevalent in the Punjab region, Northwestern Indian. Hemoglobin D-Punjab can be inherited in heterozygosis with hemoglobin A causing no clinical or hematological alterations, or in homozygosis, the rarest form of inheritance, a condition that is commonly not related to clinical symptomatology. Moreover, this variant can exist in association with other hemoglobinopathies, such as thalassemias; the most noticeable clinical alterations occur when hemoglobin D-Punjab is associated to hemoglobin S. The clinical manifestations of this association can be similar to homozygosis for hemoglobin S. Although hemoglobin D-Punjab is a common variant globally with clinical importance especially in cases of double heterozygosis, hemoglobin S/D-Punjab is still understudied. In Brazil, for example, hemoglobin D-Punjab is the third most common hemoglobin variant. Thus, this paper summarizes information about the origin, geographic distribution, characterization and occurrence of hemoglobin D-Punjab haplotypes to try to improve our knowledge of this variant. Moreover, a list of the main techniques used in its identification is provided emphasizing the importance of complementary molecular analysis for accurate diagnosis.

Twitter Demographics

The data shown below were collected from the profiles of 8 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 51 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 10 19%
Student > Master 7 13%
Researcher 7 13%
Student > Ph. D. Student 6 12%
Other 5 10%
Other 8 15%
Unknown 9 17%
Readers by discipline Count As %
Medicine and Dentistry 16 31%
Biochemistry, Genetics and Molecular Biology 12 23%
Agricultural and Biological Sciences 6 12%
Nursing and Health Professions 3 6%
Social Sciences 2 4%
Other 4 8%
Unknown 9 17%

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 October 2020.
All research outputs
#2,924,196
of 19,191,572 outputs
Outputs from Revista Brasileira de Hematologia e Hemoterapia
#13
of 259 outputs
Outputs of similar age
#50,449
of 273,567 outputs
Outputs of similar age from Revista Brasileira de Hematologia e Hemoterapia
#1
of 7 outputs
Altmetric has tracked 19,191,572 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 259 research outputs from this source. They receive a mean Attention Score of 3.8. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 273,567 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them