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The site of the bite: Leishmania interaction with macrophages, neutrophils and the extracellular matrix in the dermis

Overview of attention for article published in Parasites & Vectors, May 2016
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (69th percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

Mentioned by

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6 X users

Citations

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63 Dimensions

Readers on

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254 Mendeley
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Title
The site of the bite: Leishmania interaction with macrophages, neutrophils and the extracellular matrix in the dermis
Published in
Parasites & Vectors, May 2016
DOI 10.1186/s13071-016-1540-3
Pubmed ID
Authors

Juliana Perrone de Menezes, Elvira M. Saraiva, Bruno da Rocha-Azevedo

Abstract

Leishmania spp., the causative agents of leishmaniasis, are intracellular parasites, transmitted to humans via the bite of their sand fly vectors. Once inoculated, the promastigotes are exposed to the dermis, which is composed of extracellular matrix (ECM), growth factors and its resident cells. Promastigote forms are phagocytosed by macrophages recruited to the site of the sand fly bite, either directly or after interaction with neutrophils. Since Leishmania is an intracellular parasite, its interaction with the host ECM has been neglected as well as the immediate steps after the sand fly bite. However, promastigotes must overcome the obstacles presented by the dermis ECM in order to establish the infection. Thus, the study of the interaction between Leishmania promastigotes and ECM components as well as the earliest stages of infection are important steps to understand the establishment of the disease, and could contribute in the future to new drug developments towards leishmaniasis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 254 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 3 1%
Peru 1 <1%
United Kingdom 1 <1%
Unknown 249 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 47 19%
Student > Bachelor 42 17%
Student > Master 37 15%
Researcher 23 9%
Student > Doctoral Student 21 8%
Other 32 13%
Unknown 52 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 56 22%
Biochemistry, Genetics and Molecular Biology 46 18%
Immunology and Microbiology 33 13%
Medicine and Dentistry 22 9%
Veterinary Science and Veterinary Medicine 11 4%
Other 22 9%
Unknown 64 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 July 2016.
All research outputs
#6,387,783
of 22,869,263 outputs
Outputs from Parasites & Vectors
#1,445
of 5,471 outputs
Outputs of similar age
#91,060
of 298,976 outputs
Outputs of similar age from Parasites & Vectors
#41
of 181 outputs
Altmetric has tracked 22,869,263 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 5,471 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 298,976 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 181 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.