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Detection of metallic cobalt and chromium liver deposition following failed hip replacement using T2* and R2 magnetic resonance

Overview of attention for article published in Journal of Cardiovascular Magnetic Resonance (Taylor & Francis Ltd), May 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (76th percentile)

Mentioned by

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10 tweeters
facebook
1 Facebook page
googleplus
1 Google+ user

Citations

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16 Dimensions

Readers on

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28 Mendeley
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Title
Detection of metallic cobalt and chromium liver deposition following failed hip replacement using T2* and R2 magnetic resonance
Published in
Journal of Cardiovascular Magnetic Resonance (Taylor & Francis Ltd), May 2016
DOI 10.1186/s12968-016-0248-z
Pubmed ID
Authors

Amna Abdel-Gadir, Reshid Berber, John B. Porter, Paul D. Quinn, Deepak Suri, Peter Kellman, Alister J. Hart, James C. Moon, Charlotte Manisty, John A. Skinner

Abstract

Failed hip prostheses can cause elevated circulating cobalt and chromium levels, with rare reports of fatal systemic organ deposition, including cobalt cardiomyopathy. Although blood cobalt and chromium levels are easily measured, organ deposition is difficult to detect without invasive biopsy. The T2* magnetic resonance (MR) method is used to quantify tissue iron deposition, and plays an important role in the management of iron-loading conditions. Cobalt and chromium, like iron, also affect magnetism and are proposed MR contrast agents. We describe a case of a 44-year-old male with a failed hip implant and very elevated blood cobalt and chromium levels. Despite normal cardiac MR findings, liver T2* and R2 values were abnormal, triggering tissue biopsy. Liver tissue analysis, including X-ray fluorescence, demonstrated heavy elemental cobalt and chromium deposition in macrophages, and no detectable iron. Our case demonstrates T2* and R2 quantification of liver metal deposition in a patient with a failed hip implant. Further work is needed to investigate the role of T2* and R2 MR in the detection of metal deposition from metal on metal hip prostheses.

Twitter Demographics

The data shown below were collected from the profiles of 10 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 28 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 32%
Other 3 11%
Professor 2 7%
Professor > Associate Professor 2 7%
Student > Postgraduate 2 7%
Other 3 11%
Unknown 7 25%
Readers by discipline Count As %
Medicine and Dentistry 7 25%
Engineering 5 18%
Nursing and Health Professions 2 7%
Agricultural and Biological Sciences 1 4%
Computer Science 1 4%
Other 3 11%
Unknown 9 32%

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 February 2018.
All research outputs
#3,077,864
of 16,254,157 outputs
Outputs from Journal of Cardiovascular Magnetic Resonance (Taylor & Francis Ltd)
#229
of 1,009 outputs
Outputs of similar age
#61,524
of 266,457 outputs
Outputs of similar age from Journal of Cardiovascular Magnetic Resonance (Taylor & Francis Ltd)
#1
of 1 outputs
Altmetric has tracked 16,254,157 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,009 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.6. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 266,457 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them