Results provide a proof of concept that low amounts of drugs that generate ER and oxidative stresses combined with ATRA could be an effective targeted therapy to hit AML cells characterized by MLL fusion proteins and FLT3-ITD mutation. https://t.co/6AevjWu
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Retinoic acid synergizes with the unfolded protein response and oxidative stress to induce cell death in FLT3-ITD+ AML. https://t.co/57tAEx90k1 #Neuralstemcells
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New article: Retinoic acid synergizes with the unfolded protein response and oxidative stress to induce cell death in FLT3-ITD+ AML. https://t.co/OzG8EyqJtG #AML #leusm #hematology