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Association between overweight and obesity in schoolchildren with rs9939609 polymorphism (FTO) and family history for obesity

Overview of attention for article published in Jornal de Pediatria, September 2016
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Title
Association between overweight and obesity in schoolchildren with rs9939609 polymorphism (FTO) and family history for obesity
Published in
Jornal de Pediatria, September 2016
DOI 10.1016/j.jped.2015.11.005
Pubmed ID
Authors

Cézane Priscila Reuter, Miria Suzana Burgos, Joana Carolina Bernhard, Debora Tornquist, Elisa Inês Klinger, Tássia Silvana Borges, Jane Dagmar Pollo Renner, Andréia Rosane de Moura Valim, Elza Daniel de Mello

Abstract

To determine the association between overweight/obesity in schoolchildren with FTO rs9939609 polymorphism (fatmass and obesity associated) and family history of obesity. Cross-sectional study comprising a sample of 406 children aged 7-17 years in a city in southern Brazil. Overweight/obesity in schoolchildren was assessed by body mass index (BMI), and family history of obesity was self-reported by parents. Polymorphism genotyping was performed by real time PCR (polymerase chain reaction). The association between the nutritional status of schoolchildren with the presence of family obesity, stratified by polymorphism genotypes (AA [at-risk for obesity], AT, and TT), was assessed by prevalence ratio values (PR) through Poisson regression. Among schoolchildren with the AA genotype, 57.4% had overweight/obesity; the percentage was lower for the AT and TT genotypes (33.1% and 28.9%, respectively). Overweight/obesity in schoolchildren was associated with a family history of obesity, especially among children with the AA genotype. The prevalence was higher among those with an obese mother (PR: 1.28; p<0.001), obese maternal or paternal grandmother (PR: 1.22; p=0.047), and obese paternal grandfather (PR: 1.32; p<0.001). There is an association between the AA genotype of rs9939609 polymorphism and BMI among schoolchildren. The association between overweight/obesity in schoolchildren with a family history of obesity was found mainly among students with the AA genotype.

Twitter Demographics

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Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 18%
Student > Postgraduate 3 14%
Student > Master 2 9%
Student > Doctoral Student 1 5%
Researcher 1 5%
Other 1 5%
Unknown 10 45%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 6 27%
Medicine and Dentistry 3 14%
Nursing and Health Professions 2 9%
Sports and Recreations 1 5%
Business, Management and Accounting 1 5%
Other 0 0%
Unknown 9 41%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 May 2016.
All research outputs
#10,038,103
of 12,546,249 outputs
Outputs from Jornal de Pediatria
#306
of 419 outputs
Outputs of similar age
#182,807
of 262,367 outputs
Outputs of similar age from Jornal de Pediatria
#5
of 10 outputs
Altmetric has tracked 12,546,249 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 419 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 262,367 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.