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Biological effects of inhaled nitrogen dioxide in healthy human subjects

Overview of attention for article published in International Archives of Occupational & Environmental Health, May 2016
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#1 of 1,334)
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

Mentioned by

news
6 news outlets
blogs
1 blog
twitter
110 tweeters

Citations

dimensions_citation
1 Dimensions

Readers on

mendeley
7 Mendeley
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Title
Biological effects of inhaled nitrogen dioxide in healthy human subjects
Published in
International Archives of Occupational & Environmental Health, May 2016
DOI 10.1007/s00420-016-1139-1
Pubmed ID
Authors

Brand, P, Bertram, J, Chaker, A, Jörres, R A, Kronseder, A, Kraus, T, Gube, M, P. Brand, J. Bertram, A. Chaker, R. A. Jörres, A. Kronseder, T. Kraus, M. Gube

Abstract

Several epidemiological studies indicate that inhaled nitrogen dioxide (NO2) at low concentrations have been statistically associated with adverse health effects. However, these results are not reflected by exposure studies in humans. The aim of the study was to assess the acute functional and cellular responses to different NO2 concentrations in healthy human subjects with various techniques. Twenty-five subjects were exposed for 3 h to NO2 concentrations 0, 0.1, 0.5, and 1.5 ppm in a randomized crossover study design during 4 consecutive weeks. In each subject, lung function, diffusion capacity and exhaled nitric oxide were measured and inflammation markers were assessed in blood, nasal secretions, induced sputum and exhaled breath condensate. From all lung function indices under consideration, only intrathoracic gas volume was borderline significantly increased after 0.5 ppm (p = 0.048) compared to 0.1 ppm NO2. Regarding the cellular effect parameters, the macrophage concentration in induced sputum decreased with increasing NO2 concentration, although these changes were only borderline significant (p = 0.05). These results do not suggest a considerable acute adverse response in human subjects after 3 h of exposure to NO2 in the NO2 concentration range investigated in this study.

Twitter Demographics

The data shown below were collected from the profiles of 110 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 7 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 7 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 3 43%
Researcher 2 29%
Lecturer > Senior Lecturer 1 14%
Student > Doctoral Student 1 14%
Readers by discipline Count As %
Environmental Science 2 29%
Pharmacology, Toxicology and Pharmaceutical Science 1 14%
Unspecified 1 14%
Physics and Astronomy 1 14%
Neuroscience 1 14%
Other 1 14%

Attention Score in Context

This research output has an Altmetric Attention Score of 140. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 March 2018.
All research outputs
#81,805
of 11,794,606 outputs
Outputs from International Archives of Occupational & Environmental Health
#1
of 1,334 outputs
Outputs of similar age
#4,269
of 276,797 outputs
Outputs of similar age from International Archives of Occupational & Environmental Health
#1
of 9 outputs
Altmetric has tracked 11,794,606 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,334 research outputs from this source. They receive a mean Attention Score of 4.4. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 276,797 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them