↓ Skip to main content

Does adding intraperitoneal paclitaxel to standard intraperitoneal regimen yield incremental survival? A propensity score‐matched cohort study

Overview of attention for article published in Cancer Communications, May 2016
Altmetric Badge

Readers on

mendeley
10 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Does adding intraperitoneal paclitaxel to standard intraperitoneal regimen yield incremental survival? A propensity score‐matched cohort study
Published in
Cancer Communications, May 2016
DOI 10.1186/s40880-016-0105-3
Pubmed ID
Authors

Yen-Hou Chang, Chien-Hsing Lu, Ming-Shyen Yen, Wai-Hou Lee, Yi Chang, Wei-Pin Chang, Chi-Mu Chuang

Abstract

We recruited consecutive patients with stage III epithelial ovarian, tubal, and peritoneal cancers who had optimal residual tumor after primary cytoreductive surgery and who received intraperitoneal chemotherapy between 2002 and 2012. Two propensity score-matched sample cohorts were created. We found that the addition of paclitaxel as a second intraperitoneal agent on a 3-week dosing schedule did not yield significant incremental survival benefits over the intraperitoneal delivery of a single cisplatin-based regimen. If our findings could be confirmed by a prospective randomized study, then it would be interesting to explore the efficacy of shifting back to a dose-dense intraperitoneal delivery of paclitaxel or a dose-dense delivery of a new formulation of paclitaxel for the patients with stage III epithelial ovarian, tubal, and peritoneal cancers.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 10 100%

Demographic breakdown

Readers by professional status Count As %
Lecturer > Senior Lecturer 1 10%
Student > Doctoral Student 1 10%
Student > Bachelor 1 10%
Professor 1 10%
Student > Ph. D. Student 1 10%
Other 3 30%
Unknown 2 20%
Readers by discipline Count As %
Medicine and Dentistry 7 70%
Neuroscience 1 10%
Unknown 2 20%