Chapter title |
Biodiversity of Intestinal Lactic Acid Bacteria in the Healthy Population
|
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Chapter number | 3 |
Book title |
Advances in Microbiology, Infectious Diseases and Public Health
|
Published in |
Advances in experimental medicine and biology, May 2016
|
DOI | 10.1007/5584_2016_3 |
Pubmed ID | |
Book ISBNs |
978-3-31-943206-9, 978-3-31-943207-6
|
Authors |
Mikelsaar, Marika, Sepp, Epp, Štšepetova, Jelena, Songisepp, Epp, Mändar, Reet, Marika Mikelsaar, Epp Sepp, Jelena Štšepetova, Epp Songisepp, Reet Mändar |
Abstract |
The complex ecosystem of the gastrointestinal tract involves tight interrelations among host cells, diet, and billions of microbes, both beneficial and opportunistic pathogens. In spite of advanced genomic, metagenomic, and metabonomic approaches, knowledge is still quite limited regarding the biodiversity of beneficial microbiota, including Lactobacillus spp., and its impact on the main biomarkers of general health. In this paper, Lactobacillus biodiversity is demonstrated through its taxonomy, function, and host-microbial interactions. Its prevalence, composition, abundance, intertwined metabolic properties, and relation to host age, genotype, and socioeconomic factors are reviewed based on the literature and original research experience. The species richness, e.g., the biodiversity of gut microbiota, provides the host with a variety of metabolically active species and strains that predict their response for different health conditions and extrinsic interventions. Metabolically active and safe Lactobacillus species and specific strains with particular functional properties increase the biodiversity of the whole intestinal microbiota. The elaborated principles for effective application of probiotics are discussed, aimed at regulating the composition of microbiota simultaneously with blood and urine biomarkers at the borderline of normality. This approach targets the impact of probiotic strains to maintenance of health with anti-infectious, cardiovascular, and metabolic support. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 25% |
Unknown | 3 | 75% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 75% |
Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 61 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 9 | 15% |
Student > Master | 9 | 15% |
Student > Ph. D. Student | 7 | 11% |
Other | 5 | 8% |
Student > Bachelor | 4 | 7% |
Other | 8 | 13% |
Unknown | 19 | 31% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 11 | 18% |
Biochemistry, Genetics and Molecular Biology | 8 | 13% |
Medicine and Dentistry | 6 | 10% |
Immunology and Microbiology | 5 | 8% |
Nursing and Health Professions | 2 | 3% |
Other | 6 | 10% |
Unknown | 23 | 38% |