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Distinct transcriptional outputs associated with mono- and dimethylated histone H3 arginine 2

Overview of attention for article published in Nature Structural & Molecular Biology, March 2009
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (70th percentile)
  • Good Attention Score compared to outputs of the same age and source (65th percentile)

Mentioned by

twitter
1 tweeter
wikipedia
1 Wikipedia page

Citations

dimensions_citation
42 Dimensions

Readers on

mendeley
67 Mendeley
citeulike
1 CiteULike
connotea
2 Connotea
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Title
Distinct transcriptional outputs associated with mono- and dimethylated histone H3 arginine 2
Published in
Nature Structural & Molecular Biology, March 2009
DOI 10.1038/nsmb.1569
Pubmed ID
Authors

Antonis Kirmizis, Helena Santos-Rosa, Christopher J Penkett, Michael A Singer, Roland D Green, Tony Kouzarides

Abstract

Dimethylation of histone H3 Arg2 (H3R2me2) maintains transcriptional silencing by inhibiting Set1 mediated trimethylation of H3K4. Here we demonstrate that Arg2 is also monomethylated (H3R2me1) in yeast but that its functional characteristics are distinct from H3R2me2: (i) H3R2me1 does not inhibit histone H3 Lys4 (H3K4) methylation; (ii) it is present throughout the coding region of genes; and (iii) it correlates with active transcription. Collectively, these results indicate that different H3R2 methylation states have defined roles in gene expression.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
India 1 1%
United Kingdom 1 1%
Unknown 63 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 23 34%
Student > Ph. D. Student 18 27%
Professor 8 12%
Professor > Associate Professor 5 7%
Student > Bachelor 5 7%
Other 6 9%
Unknown 2 3%
Readers by discipline Count As %
Agricultural and Biological Sciences 47 70%
Biochemistry, Genetics and Molecular Biology 13 19%
Chemistry 3 4%
Medicine and Dentistry 2 3%
Arts and Humanities 1 1%
Other 0 0%
Unknown 1 1%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 March 2019.
All research outputs
#4,275,709
of 14,501,785 outputs
Outputs from Nature Structural & Molecular Biology
#1,438
of 2,679 outputs
Outputs of similar age
#34,976
of 124,059 outputs
Outputs of similar age from Nature Structural & Molecular Biology
#14
of 41 outputs
Altmetric has tracked 14,501,785 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 2,679 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.6. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 124,059 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.