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H3K4me3 inversely correlates with DNA methylation at a large class of non-CpG-island containing start sites

Overview of attention for article published in Genome Medicine, May 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (91st percentile)
  • High Attention Score compared to outputs of the same age and source (82nd percentile)

Mentioned by

blogs
1 blog
twitter
6 tweeters

Citations

dimensions_citation
32 Dimensions

Readers on

mendeley
59 Mendeley
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Title
H3K4me3 inversely correlates with DNA methylation at a large class of non-CpG-island containing start sites
Published in
Genome Medicine, May 2012
DOI 10.1186/gm346
Pubmed ID
Authors

Dheepa Balasubramanian, Batool Akhtar-Zaidi, Lingyun Song, Cynthia F Bartels, Martina Veigl, Lydia Beard, Lois Myeroff, Kishore Guda, James Lutterbaugh, Joseph Willis, Gregory E Crawford, Sanford D Markowitz, Peter C Scacheri, Balasubramanian D, Akhtar-Zaidi B, Song L, Bartels CF, Veigl M, Beard L, Myeroff L, Guda K, Lutterbaugh J, Willis J, Crawford GE, Markowitz SD, Scacheri PC

Abstract

In addition to mutations, epigenetic silencing of genes has been recognized as a fundamental mechanism that promotes human carcinogenesis. To date, characterization of epigenetic gene silencing has largely focused on genes in which silencing is mediated by hypermethylation of promoter-associated CpG islands, associated with loss of the H3K4me3 chromatin mark. Far less is known about promoters lacking CpG-islands or genes that are repressed by alternative mechanisms.

Twitter Demographics

The data shown below were collected from the profiles of 6 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Chile 1 2%
United States 1 2%
Netherlands 1 2%
Unknown 55 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 29%
Researcher 14 24%
Student > Doctoral Student 6 10%
Student > Bachelor 5 8%
Student > Postgraduate 4 7%
Other 11 19%
Unknown 2 3%
Readers by discipline Count As %
Agricultural and Biological Sciences 36 61%
Biochemistry, Genetics and Molecular Biology 13 22%
Medicine and Dentistry 6 10%
Mathematics 2 3%
Unknown 2 3%

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 June 2012.
All research outputs
#1,010,978
of 11,342,375 outputs
Outputs from Genome Medicine
#315
of 837 outputs
Outputs of similar age
#9,451
of 106,879 outputs
Outputs of similar age from Genome Medicine
#4
of 23 outputs
Altmetric has tracked 11,342,375 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 837 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 22.4. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 106,879 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.