Tau Biology

Table of Contents

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   Book Overview
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   Chapter 1 Ordered Assembly of Tau Protein and Neurodegeneration
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   Chapter 2 Structure of NFT: Biochemical Approach
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   Chapter 3 Nuclear Magnetic Resonance Spectroscopy Insights into Tau Structure in Solution: Impact of Post-translational Modifications
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   Chapter 4 Regulation of Tau Homeostasis and Toxicity by Acetylation
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   Chapter 5 Tau Clearance Mechanisms
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   Chapter 6 Mechanisms of Axonal Sorting of Tau and Influence of the Axon Initial Segment on Tau Cell Polarity
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   Chapter 7 Tau and Axonal Transport Misregulation in Tauopathies
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   Chapter 8 Presynaptic Pathophysiology Encoded in Different Domains of Tau – Hyper-Versus Hypoexcitability?
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    Chapter 9 Synaptic Localisation of Tau
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    Chapter 10 The Role of Tau in the Post-synapse
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    Chapter 11 Tau Secretion
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    Chapter 12 Emerging Connections Between Tau and Nucleic Acids
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    Chapter 13 Tau Interacting Proteins: Gaining Insight into the Roles of Tau in Health and Disease
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    Chapter 14 Relationship Between Tau, β Amyloid and α-Synuclein Pathologies
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    Chapter 15 Associations Between APOE Variants, Tau and α-Synuclein
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    Chapter 16 Amyloid-β and Tau at the Crossroads of Alzheimer’s Disease
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    Chapter 17 Myotonic Dystrophy: an RNA Toxic Gain of Function Tauopathy?
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    Chapter 18 Tau PET Imaging
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    Chapter 19 Tau Accumulation and Network Breakdown in Alzheimer’s Disease
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    Chapter 20 Stress and the Etiopathogenesis of Alzheimer’s Disease and Depression
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    Chapter 21 Tau, Diabetes and Insulin
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    Chapter 22 Top-Down Projections Direct the Gradual Progression of Alzheimer-Related Tau Pathology Throughout the Neocortex
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    Chapter 23 Tau Prion-Like Propagation: State of the Art and Current Challenges
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    Chapter 24 Tau Condensates
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    Chapter 25 Liquid-Liquid Phase Separation of Tau Protein in Neurobiology and Pathology
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    Chapter 26 The Pathophysiology of Tau and Stress Granules in Disease
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    Chapter 27 Tau Oligomers
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    Chapter 28 Experimental Models of Tauopathy – From Mechanisms to Therapies
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    Chapter 29 Cerebrospinal Fluid and Plasma Tau as a Biomarker for Brain Tauopathy
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    Chapter 30 Dementia Therapy Targeting Tau