@Biotech2k1 @danhart5012 Donors could be a superior source of reactive TCRs. So in combination with sequencing of CTCs and/or ctDNA, it is conceivable that identification of both neoantigens and reactive receptors could be achievable solely from blood in t
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@AndriyCherpakov @Scorpionblue13 @beercules47 @Biotech2k1 @BioEqman Using matched donors would be an interesting approach. In this paper they found that eleven out of the selected neoantigen candidates elicited reactivity from the donors. In contrast, resp
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It's a very nice (but rare) example where there is immunological thinking behind design of CAR T cells, it's cool to see this project funded. Reference article: https://t.co/UuLXxRCKFw
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@ChrisHeery @ad1600 Am not surprised at this, not after Schumacher’s fascinating research a couple of years ago: https://t.co/qS5lwA7WwX