@SabinehazanMD @WildColonialGal @Fynnderella1 @HouseLyndseyRN @Jikkyleaks @PierreKory @Progenabiome https://t.co/BVMfCTZYD8. GABA is located throughout the GI tract and is found in enteric nerves as well as in endocrine-like cells, implicating GABA as bot
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https://t.co/ZI91YDHBYy "Therefore, the functional effects of GABAB receptors are likely to differ along the GI tract, and are likely to be dependant on its colocalization with prominent enteroendocrine cell mediators such as somatostatin and serotonin."
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https://t.co/ZI91YDHBYy "Both gastric and intestinal regions displayed mucosal GABAB immunoreacticity, however gastric GABAB-positive cells tended to contain somatostatin, in contrast to duodenal GABAB positive cells which stained positively for serotonin
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https://t.co/ZI91YDHBYy "Additionally, GABA-mediated inhibition of GI motility appears to be dependant on the GABAB1 receptor subunit."