Title |
Diffuse large B-cell lymphoma in an adolescent female presenting with Epstein-Barr virus-driven hemophagocytic lymphohistiocytosis: a case report
|
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Published in |
Journal of Medical Case Reports, June 2012
|
DOI | 10.1186/1752-1947-6-141 |
Pubmed ID | |
Authors |
Sadaf Altaf, Grace M Atreaga, Avni Y Joshi, Vilmarie Rodriguez |
Abstract |
Hemophagocytic lymphohistiocytosis is characterized by multisystem inflammation, resulting from prolonged and intense activation of macrophages, histiocytes and CD8+ T-cells. Due to its variable presentation and non-specific findings, timely diagnosis can be challenging. This condition has been associated with malignancies, most commonly with lymphomas and leukemias of T-cell lineage. This case report represents the less commonly associated B-cell lymphomas. We also highlight the difficulties in managing hemophagocytosis with an evolving malignancy. This case report will add to the increasing literature on the diagnosis, complications and management of this complex disorder. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Italy | 1 | 4% |
Unknown | 25 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 4 | 15% |
Other | 3 | 12% |
Student > Doctoral Student | 2 | 8% |
Student > Postgraduate | 2 | 8% |
Professor | 1 | 4% |
Other | 2 | 8% |
Unknown | 12 | 46% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 10 | 38% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
Agricultural and Biological Sciences | 1 | 4% |
Nursing and Health Professions | 1 | 4% |
Social Sciences | 1 | 4% |
Other | 1 | 4% |
Unknown | 11 | 42% |