Title |
Interactive effects of neonatal exposure to monosodium glutamate and aspartame on glucose homeostasis
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Published in |
Nutrition & Metabolism, June 2012
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DOI | 10.1186/1743-7075-9-58 |
Pubmed ID | |
Authors |
Kate S Collison, Nadine J Makhoul, Marya Z Zaidi, Rana Al-Rabiah, Angela Inglis, Bernard L Andres, Rosario Ubungen, Mohammed Shoukri, Futwan A Al-Mohanna |
Abstract |
Recent evidence suggests that the effects of certain food additives may be synergistic or additive. Aspartame (ASP) and Monosodium Glutamate (MSG) are ubiquitous food additives with a common moiety: both contain acidic amino acids which can act as neurotransmitters, interacting with NMDA receptors concentrated in areas of the Central Nervous System regulating energy expenditure and conservation. MSG has been shown to promote a neuroendocrine dysfunction when large quantities are administered to mammals during the neonatal period. ASP is a low-calorie dipeptide sweetener found in a wide variety of diet beverages and foods. However, recent reports suggest that ASP may promote weight gain and hyperglycemia in a zebrafish nutritional model. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 14% |
United Kingdom | 2 | 9% |
Canada | 2 | 9% |
Germany | 1 | 5% |
Netherlands | 1 | 5% |
Norway | 1 | 5% |
Cameroon | 1 | 5% |
Sweden | 1 | 5% |
Unknown | 10 | 45% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 14 | 64% |
Practitioners (doctors, other healthcare professionals) | 5 | 23% |
Scientists | 3 | 14% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 2% |
Saudi Arabia | 1 | <1% |
Unknown | 119 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 26 | 21% |
Student > Master | 17 | 14% |
Researcher | 12 | 10% |
Student > Ph. D. Student | 10 | 8% |
Other | 8 | 7% |
Other | 20 | 16% |
Unknown | 29 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 26 | 21% |
Medicine and Dentistry | 17 | 14% |
Nursing and Health Professions | 13 | 11% |
Biochemistry, Genetics and Molecular Biology | 13 | 11% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 4% |
Other | 14 | 11% |
Unknown | 34 | 28% |