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Bacteria in cancer therapy: a novel experimental strategy

Overview of attention for article published in Journal of Biomedical Science, January 2010
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#18 of 787)
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

blogs
1 blog
twitter
6 tweeters
patent
7 patents
facebook
1 Facebook page
wikipedia
1 Wikipedia page
googleplus
1 Google+ user
linkedin
1 LinkedIn user
video
1 video uploader

Citations

dimensions_citation
158 Dimensions

Readers on

mendeley
456 Mendeley
citeulike
3 CiteULike
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Title
Bacteria in cancer therapy: a novel experimental strategy
Published in
Journal of Biomedical Science, January 2010
DOI 10.1186/1423-0127-17-21
Pubmed ID
Authors

S Patyar, R Joshi, DS Prasad Byrav, A Prakash, B Medhi, BK Das

Abstract

Resistance to conventional anticancer therapies in patients with advanced solid tumors has prompted the need of alternative cancer therapies. Moreover, the success of novel cancer therapies depends on their selectivity for cancer cells with limited toxicity to normal tissues. Several decades after Coley's work a variety of natural and genetically modified non-pathogenic bacterial species are being explored as potential antitumor agents, either to provide direct tumoricidal effects or to deliver tumoricidal molecules. Live, attenuated or genetically modified non-pathogenic bacterial species are capable of multiplying selectively in tumors and inhibiting their growth. Due to their selectivity for tumor tissues, these bacteria and their spores also serve as ideal vectors for delivering therapeutic proteins to tumors. Bacterial toxins too have emerged as promising cancer treatment strategy. The most potential and promising strategy is bacteria based gene-directed enzyme prodrug therapy. Although it has shown successful results in vivo yet further investigation about the targeting mechanisms of the bacteria are required to make it a complete therapeutic approach in cancer treatment.

Twitter Demographics

The data shown below were collected from the profiles of 6 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 456 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 <1%
Germany 2 <1%
Brazil 2 <1%
South Africa 1 <1%
Malaysia 1 <1%
France 1 <1%
India 1 <1%
United Kingdom 1 <1%
Iran, Islamic Republic of 1 <1%
Other 2 <1%
Unknown 442 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 110 24%
Student > Master 88 19%
Student > Bachelor 75 16%
Researcher 55 12%
Student > Postgraduate 22 5%
Other 65 14%
Unknown 41 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 159 35%
Biochemistry, Genetics and Molecular Biology 99 22%
Medicine and Dentistry 37 8%
Immunology and Microbiology 32 7%
Engineering 19 4%
Other 51 11%
Unknown 59 13%

Attention Score in Context

This research output has an Altmetric Attention Score of 28. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 January 2021.
All research outputs
#840,672
of 16,968,502 outputs
Outputs from Journal of Biomedical Science
#18
of 787 outputs
Outputs of similar age
#5,394
of 131,784 outputs
Outputs of similar age from Journal of Biomedical Science
#1
of 7 outputs
Altmetric has tracked 16,968,502 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 787 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 131,784 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them