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Bacteria in cancer therapy: a novel experimental strategy

Overview of attention for article published in Journal of Biomedical Science, January 2010
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#10 of 659)
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

blogs
1 blog
twitter
6 tweeters
patent
4 patents
facebook
1 Facebook page
googleplus
1 Google+ user
linkedin
1 LinkedIn user
video
1 video uploader

Citations

dimensions_citation
146 Dimensions

Readers on

mendeley
416 Mendeley
citeulike
3 CiteULike
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Title
Bacteria in cancer therapy: a novel experimental strategy
Published in
Journal of Biomedical Science, January 2010
DOI 10.1186/1423-0127-17-21
Pubmed ID
Authors

S Patyar, R Joshi, DS Prasad Byrav, A Prakash, B Medhi, BK Das

Abstract

Resistance to conventional anticancer therapies in patients with advanced solid tumors has prompted the need of alternative cancer therapies. Moreover, the success of novel cancer therapies depends on their selectivity for cancer cells with limited toxicity to normal tissues. Several decades after Coley's work a variety of natural and genetically modified non-pathogenic bacterial species are being explored as potential antitumor agents, either to provide direct tumoricidal effects or to deliver tumoricidal molecules. Live, attenuated or genetically modified non-pathogenic bacterial species are capable of multiplying selectively in tumors and inhibiting their growth. Due to their selectivity for tumor tissues, these bacteria and their spores also serve as ideal vectors for delivering therapeutic proteins to tumors. Bacterial toxins too have emerged as promising cancer treatment strategy. The most potential and promising strategy is bacteria based gene-directed enzyme prodrug therapy. Although it has shown successful results in vivo yet further investigation about the targeting mechanisms of the bacteria are required to make it a complete therapeutic approach in cancer treatment.

Twitter Demographics

The data shown below were collected from the profiles of 6 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 416 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 <1%
Germany 2 <1%
Brazil 2 <1%
South Africa 1 <1%
Malaysia 1 <1%
France 1 <1%
India 1 <1%
United Kingdom 1 <1%
Iran, Islamic Republic of 1 <1%
Other 2 <1%
Unknown 402 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 106 25%
Student > Master 83 20%
Student > Bachelor 69 17%
Researcher 53 13%
Student > Postgraduate 20 5%
Other 59 14%
Unknown 26 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 153 37%
Biochemistry, Genetics and Molecular Biology 94 23%
Medicine and Dentistry 36 9%
Immunology and Microbiology 28 7%
Engineering 18 4%
Other 46 11%
Unknown 41 10%

Attention Score in Context

This research output has an Altmetric Attention Score of 22. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 November 2017.
All research outputs
#747,567
of 13,537,409 outputs
Outputs from Journal of Biomedical Science
#10
of 659 outputs
Outputs of similar age
#6,021
of 121,594 outputs
Outputs of similar age from Journal of Biomedical Science
#1
of 11 outputs
Altmetric has tracked 13,537,409 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 659 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 121,594 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.