Title |
Type of anaesthesia and the safety and efficacy of thromboprophylaxis with enoxaparin or dabigatran etexilate in major orthopaedic surgery: pooled analysis of three randomized controlled trials
|
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Published in |
Thrombosis Journal, June 2012
|
DOI | 10.1186/1477-9560-10-9 |
Pubmed ID | |
Authors |
Nadia Rosencher, Herbert Noack, Martin Feuring, Andreas Clemens, Richard J Friedman, Bengt I Eriksson |
Abstract |
There has been a shift towards greater use of neuraxial over general anaesthesia for patients undergoing total hip or knee arthroplasty. Furthermore, suggestions that peripheral nerve block may reduce adverse effects have recently been put forward. Although older studies showed a reduction in venous thromboembolism (VTE) with neuraxial compared with general anaesthesia, this difference has not been confirmed in studies using effective current thromboprophylaxis. We used a large data set to investigate the pattern of anaesthesia usage, and whether anaesthesia type affects efficacy and bleeding outcomes of thromboprophylaxis overall, within each treatment group, or for the novel oral anticoagulant dabigatran etexilate versus enoxaparin. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Chile | 1 | 2% |
Slovenia | 1 | 2% |
Unknown | 39 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 7 | 17% |
Student > Bachelor | 5 | 12% |
Student > Doctoral Student | 4 | 10% |
Other | 3 | 7% |
Researcher | 3 | 7% |
Other | 12 | 29% |
Unknown | 7 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 22 | 54% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 5% |
Agricultural and Biological Sciences | 2 | 5% |
Nursing and Health Professions | 2 | 5% |
Social Sciences | 2 | 5% |
Other | 2 | 5% |
Unknown | 9 | 22% |