Title |
Serum glutamine, set-shifting ability and anorexia nervosa
|
---|---|
Published in |
Annals of General Psychiatry, June 2010
|
DOI | 10.1186/1744-859x-9-29 |
Pubmed ID | |
Authors |
Michiko Nakazato, Kenji Hashimoto, Ulrike Schmidt, Kate Tchanturia, Iain C Campbell, David A Collier, Masaomi Iyo, Janet Treasure |
Abstract |
Set-shifting is impaired in people with anorexia nervosa (AN), but the underlying physiological and biochemical processes are unclear. Animal studies have established that glutamatergic pathways in the prefrontal cortex play an important role in set-shifting ability. However, it is not yet understood whether levels of serum glutamatergic amino acids are associated with set-shifting performance in humans. The aim of this study was to determine whether serum concentrations of amino acids related to glutamatergic neurotransmission (glutamine, glutamate, glycine, l-serine, d-serine) are associated with set-shifting ability in people with acute AN and those after recovery. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 1% |
Unknown | 79 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 14 | 18% |
Student > Ph. D. Student | 12 | 15% |
Student > Doctoral Student | 9 | 11% |
Other | 8 | 10% |
Student > Bachelor | 7 | 9% |
Other | 19 | 24% |
Unknown | 11 | 14% |
Readers by discipline | Count | As % |
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Psychology | 23 | 29% |
Medicine and Dentistry | 18 | 23% |
Neuroscience | 9 | 11% |
Agricultural and Biological Sciences | 7 | 9% |
Nursing and Health Professions | 3 | 4% |
Other | 8 | 10% |
Unknown | 12 | 15% |