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A nicotinic hypothesis for Covid-19 with preventive and therapeutic implications

Overview of attention for article published in Qeios, April 2020
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#3 of 432)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Readers on

mendeley
17 Mendeley
Title
A nicotinic hypothesis for Covid-19 with preventive and therapeutic implications
Published in
Qeios, April 2020
DOI 10.32388/fxgqsb
Authors

jean-pierre CHANGEUX, Zahir Amoura, Felix Rey, Makoto Miyara

Abstract

SARS-CoV-2 epidemics raises a considerable issue of public health at the planetary scale. There is a pressing urgency to find treatments based upon currently available scientific knowledge. Therefore, we tentatively propose a hypothesis which hopefully might ultimately help saving lives. Based on the current scientific literature and on new epidemiological data which reveal that current smoking status appears to be a protective factor against the infection by SARS-CoV-2 [1], we hypothesize that the nicotinic acetylcholine receptor (nAChR) plays a key role in the pathophysiology of Covid-19 infection and might represent a target for the prevention and control of Covid-19 infection.

Twitter Demographics

The data shown below were collected from the profiles of 905 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 3 18%
Other 2 12%
Student > Doctoral Student 2 12%
Professor 1 6%
Student > Ph. D. Student 1 6%
Other 2 12%
Unknown 6 35%
Readers by discipline Count As %
Medicine and Dentistry 3 18%
Social Sciences 2 12%
Nursing and Health Professions 2 12%
Arts and Humanities 1 6%
Pharmacology, Toxicology and Pharmaceutical Science 1 6%
Other 2 12%
Unknown 6 35%

Attention Score in Context

This research output has an Altmetric Attention Score of 2116. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 June 2022.
All research outputs
#3,112
of 21,421,530 outputs
Outputs from Qeios
#3
of 432 outputs
Outputs of similar age
#254
of 296,118 outputs
Outputs of similar age from Qeios
#1
of 8 outputs
Altmetric has tracked 21,421,530 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 432 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 24.6. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 296,118 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them